Pharmacokinetics, Pharmacodynamics, and Dosing Considerations of Novel β-Lactams and β-Lactam/β-Lactamase Inhibitors in Critically Ill Adult Patients: Focus on Obesity, Augmented Renal Clearance, Renal Replacement Therapies, and Extracorporeal Membrane Oxygenation

Objective: Dose optimization of novel β-lactam antibiotics (NBLA) has become necessary given the increased prevalence of multidrug-resistant infections in intensive care units coupled with the limited number of available treatment options. Unfortunately, recommended dose regimens of NBLA based on PK...

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Detalles Bibliográficos
Autores principales: Bakdach, Dana, Elajez, Reem, Bakdach, Abdul Rahman, Awaisu, Ahmed, De Pascale, Gennaro, Ait Hssain, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738279/
https://www.ncbi.nlm.nih.gov/pubmed/36498473
http://dx.doi.org/10.3390/jcm11236898

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