Cargando…
Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review
Endometriosis is a systemic medical condition characterized by endometrial tissue that is abnormally implanted in extrauterine sites, including the central nervous system. In this article, we reported the case of a patient with presumed cerebral endometriosis who was diagnosed with bipolar disorder...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738496/ https://www.ncbi.nlm.nih.gov/pubmed/36498786 http://dx.doi.org/10.3390/jcm11237212 |
_version_ | 1784847558244302848 |
---|---|
author | Elefante, Camilla Brancati, Giulio Emilio Oragvelidze, Elene Lattanzi, Lorenzo Maremmani, Icro Perugi, Giulio |
author_facet | Elefante, Camilla Brancati, Giulio Emilio Oragvelidze, Elene Lattanzi, Lorenzo Maremmani, Icro Perugi, Giulio |
author_sort | Elefante, Camilla |
collection | PubMed |
description | Endometriosis is a systemic medical condition characterized by endometrial tissue that is abnormally implanted in extrauterine sites, including the central nervous system. In this article, we reported the case of a patient with presumed cerebral endometriosis who was diagnosed with bipolar disorder and panic disorder and systematically reviewed the literature for previously reported neuropsychiatric symptoms in patients with cerebral and cerebellar endometriosis. The PubMed, Scopus, and Web of Science bibliographic databases were searched according to the PRISMA guidelines. Seven previous case reports were found and described. While neurological disturbances dominated the clinical picture in the cases retrieved from the literature, our patient represented the first case to show both neurological and psychiatric manifestations. Atypical features of bipolar disorder including chronic mood instability, mixed episodes, and excitatory interepisodic symptoms were highlighted. During the neuropsychological evaluation, a dysexecutive profile consistent with frontal lobe pathology was evidenced. We hypothesized that the course and features of the illness were largely influenced by the presence of documented brain lesions compatible with endometrial implants, especially in the frontal region. Accordingly, patients with endometriosis who exhibit neurological as well as mental symptoms should be investigated for cerebral lesions. |
format | Online Article Text |
id | pubmed-9738496 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97384962022-12-11 Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review Elefante, Camilla Brancati, Giulio Emilio Oragvelidze, Elene Lattanzi, Lorenzo Maremmani, Icro Perugi, Giulio J Clin Med Review Endometriosis is a systemic medical condition characterized by endometrial tissue that is abnormally implanted in extrauterine sites, including the central nervous system. In this article, we reported the case of a patient with presumed cerebral endometriosis who was diagnosed with bipolar disorder and panic disorder and systematically reviewed the literature for previously reported neuropsychiatric symptoms in patients with cerebral and cerebellar endometriosis. The PubMed, Scopus, and Web of Science bibliographic databases were searched according to the PRISMA guidelines. Seven previous case reports were found and described. While neurological disturbances dominated the clinical picture in the cases retrieved from the literature, our patient represented the first case to show both neurological and psychiatric manifestations. Atypical features of bipolar disorder including chronic mood instability, mixed episodes, and excitatory interepisodic symptoms were highlighted. During the neuropsychological evaluation, a dysexecutive profile consistent with frontal lobe pathology was evidenced. We hypothesized that the course and features of the illness were largely influenced by the presence of documented brain lesions compatible with endometrial implants, especially in the frontal region. Accordingly, patients with endometriosis who exhibit neurological as well as mental symptoms should be investigated for cerebral lesions. MDPI 2022-12-04 /pmc/articles/PMC9738496/ /pubmed/36498786 http://dx.doi.org/10.3390/jcm11237212 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Elefante, Camilla Brancati, Giulio Emilio Oragvelidze, Elene Lattanzi, Lorenzo Maremmani, Icro Perugi, Giulio Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review |
title | Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review |
title_full | Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review |
title_fullStr | Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review |
title_full_unstemmed | Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review |
title_short | Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review |
title_sort | psychiatric symptoms in patients with cerebral endometriosis: a case report and literature review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738496/ https://www.ncbi.nlm.nih.gov/pubmed/36498786 http://dx.doi.org/10.3390/jcm11237212 |
work_keys_str_mv | AT elefantecamilla psychiatricsymptomsinpatientswithcerebralendometriosisacasereportandliteraturereview AT brancatigiulioemilio psychiatricsymptomsinpatientswithcerebralendometriosisacasereportandliteraturereview AT oragvelidzeelene psychiatricsymptomsinpatientswithcerebralendometriosisacasereportandliteraturereview AT lattanzilorenzo psychiatricsymptomsinpatientswithcerebralendometriosisacasereportandliteraturereview AT maremmaniicro psychiatricsymptomsinpatientswithcerebralendometriosisacasereportandliteraturereview AT perugigiulio psychiatricsymptomsinpatientswithcerebralendometriosisacasereportandliteraturereview |