Bromodomain Protein BRD4-Mediated Mutant p53 Transcription Promotes TNBC Progression

TP53 is the most common mutated gene in human cancer. Mutant p53 protein loses its tumor-suppressor properties and gains oncogenic activity. Mutant p53 is a therapeutic target in a broad range of cancer types. However, how mutant p53 is epigenetically regulated during tumor progression remains elusi...

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Detalles Bibliográficos
Autores principales: Zhou, Julie Xia, Agborbesong, Ewud, Li, Linda Xiaoyan, Li, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738555/
https://www.ncbi.nlm.nih.gov/pubmed/36499487
http://dx.doi.org/10.3390/ijms232315163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738555/
https://www.ncbi.nlm.nih.gov/pubmed/36499487
http://dx.doi.org/10.3390/ijms232315163

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