Validation of Promoters and Codon Optimization on CRISPR/Cas9-Engineered Jurkat Cells Stably Expressing αRep4E3 for Interfering with HIV-1 Replication

Persistent and efficient therapeutic protein expression in the specific target cell is a significant concern in gene therapy. The controllable integration site, suitable promoter, and proper codon usage influence the effectiveness of the therapeutic outcome. Previously, we developed a non-immunoglob...

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Detalles Bibliográficos
Autores principales: Chupradit, Koollawat, Sornsuwan, Kanokporn, Saiprayong, Kritayaporn, Wattanapanitch, Methichit, Tayapiwatana, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738563/
https://www.ncbi.nlm.nih.gov/pubmed/36499376
http://dx.doi.org/10.3390/ijms232315049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738563/
https://www.ncbi.nlm.nih.gov/pubmed/36499376
http://dx.doi.org/10.3390/ijms232315049

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