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Validation of Promoters and Codon Optimization on CRISPR/Cas9-Engineered Jurkat Cells Stably Expressing αRep4E3 for Interfering with HIV-1 Replication

Persistent and efficient therapeutic protein expression in the specific target cell is a significant concern in gene therapy. The controllable integration site, suitable promoter, and proper codon usage influence the effectiveness of the therapeutic outcome. Previously, we developed a non-immunoglob...

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Detalles Bibliográficos
Autores principales:	Chupradit, Koollawat, Sornsuwan, Kanokporn, Saiprayong, Kritayaporn, Wattanapanitch, Methichit, Tayapiwatana, Chatchai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738563/ https://www.ncbi.nlm.nih.gov/pubmed/36499376 http://dx.doi.org/10.3390/ijms232315049

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