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Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand
Legumes and pulses are important food components with various phytochemicals and health benefits. However, the health-related bioactivities of some underutilized species remain uninvestigated. To breed a new bean lineage with particular health-related properties, this study investigated phenolics (s...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738633/ https://www.ncbi.nlm.nih.gov/pubmed/36496713 http://dx.doi.org/10.3390/foods11233905 |
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author | Chupeerach, Chaowanee Temviriyanukul, Piya Thangsiri, Sirinapa Inthachat, Woorawee Sahasakul, Yuraporn Aursalung, Amornrat Wongchang, Pitthaya Sangkasa-ad, Parichart Wongpia, Aphinya Polpanit, Auytin Nuchuchua, Onanong Suttisansanee, Uthaiwan |
author_facet | Chupeerach, Chaowanee Temviriyanukul, Piya Thangsiri, Sirinapa Inthachat, Woorawee Sahasakul, Yuraporn Aursalung, Amornrat Wongchang, Pitthaya Sangkasa-ad, Parichart Wongpia, Aphinya Polpanit, Auytin Nuchuchua, Onanong Suttisansanee, Uthaiwan |
author_sort | Chupeerach, Chaowanee |
collection | PubMed |
description | Legumes and pulses are important food components with various phytochemicals and health benefits. However, the health-related bioactivities of some underutilized species remain uninvestigated. To breed a new bean lineage with particular health-related properties, this study investigated phenolics (specifically, isoflavones) and the in vitro inhibitory activities of the enzyme relevant to some non-communicable diseases in underutilized cultivars of Phaseolus lunatus (lima beans), compared to the commonly consumed P. vulgaris (red kidney bean) and beans in the Glycine and Vigna genera. The results indicated that soybeans in the Glycine genus contained the highest isoflavone contents, especially glycitein (1825–2633 mg/100 g bean) and daidzein (1153–6471 mg/100 g bean), leading to potentially higher enzyme inhibitory activities (25–26% inhibition against α-amylase, 54–60% inhibition against α-glucosidase, 42–46% inhibition against dipeptidyl peptidase IV, 12–19% inhibition against acetylcholinesterase and 20–23% inhibition against butyrylcholinesterase) than those from other genera. Interestingly, lima beans with low isoflavone content (up to 2 mg/100 g bean) still possessed high inhibitory activities against lipase (12–21% inhibition) and β-secretase (50–58% inhibition), suggesting that bioactive compounds other than the isoflavones might be responsible for these activities. Isoflavone contents and enzyme inhibitory activities in Vigna beans were diverse, depending on the particular cultivars. The information gained from this study can be used for further investigation of bioactive components and in-depth health properties, as well as for future breeding of a new lineage of bean with specific health potentials. |
format | Online Article Text |
id | pubmed-9738633 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97386332022-12-11 Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand Chupeerach, Chaowanee Temviriyanukul, Piya Thangsiri, Sirinapa Inthachat, Woorawee Sahasakul, Yuraporn Aursalung, Amornrat Wongchang, Pitthaya Sangkasa-ad, Parichart Wongpia, Aphinya Polpanit, Auytin Nuchuchua, Onanong Suttisansanee, Uthaiwan Foods Article Legumes and pulses are important food components with various phytochemicals and health benefits. However, the health-related bioactivities of some underutilized species remain uninvestigated. To breed a new bean lineage with particular health-related properties, this study investigated phenolics (specifically, isoflavones) and the in vitro inhibitory activities of the enzyme relevant to some non-communicable diseases in underutilized cultivars of Phaseolus lunatus (lima beans), compared to the commonly consumed P. vulgaris (red kidney bean) and beans in the Glycine and Vigna genera. The results indicated that soybeans in the Glycine genus contained the highest isoflavone contents, especially glycitein (1825–2633 mg/100 g bean) and daidzein (1153–6471 mg/100 g bean), leading to potentially higher enzyme inhibitory activities (25–26% inhibition against α-amylase, 54–60% inhibition against α-glucosidase, 42–46% inhibition against dipeptidyl peptidase IV, 12–19% inhibition against acetylcholinesterase and 20–23% inhibition against butyrylcholinesterase) than those from other genera. Interestingly, lima beans with low isoflavone content (up to 2 mg/100 g bean) still possessed high inhibitory activities against lipase (12–21% inhibition) and β-secretase (50–58% inhibition), suggesting that bioactive compounds other than the isoflavones might be responsible for these activities. Isoflavone contents and enzyme inhibitory activities in Vigna beans were diverse, depending on the particular cultivars. The information gained from this study can be used for further investigation of bioactive components and in-depth health properties, as well as for future breeding of a new lineage of bean with specific health potentials. MDPI 2022-12-03 /pmc/articles/PMC9738633/ /pubmed/36496713 http://dx.doi.org/10.3390/foods11233905 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chupeerach, Chaowanee Temviriyanukul, Piya Thangsiri, Sirinapa Inthachat, Woorawee Sahasakul, Yuraporn Aursalung, Amornrat Wongchang, Pitthaya Sangkasa-ad, Parichart Wongpia, Aphinya Polpanit, Auytin Nuchuchua, Onanong Suttisansanee, Uthaiwan Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand |
title | Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand |
title_full | Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand |
title_fullStr | Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand |
title_full_unstemmed | Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand |
title_short | Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand |
title_sort | phenolic profiles and bioactivities of ten original lineage beans in thailand |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738633/ https://www.ncbi.nlm.nih.gov/pubmed/36496713 http://dx.doi.org/10.3390/foods11233905 |
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