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Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand

Legumes and pulses are important food components with various phytochemicals and health benefits. However, the health-related bioactivities of some underutilized species remain uninvestigated. To breed a new bean lineage with particular health-related properties, this study investigated phenolics (s...

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Autores principales: Chupeerach, Chaowanee, Temviriyanukul, Piya, Thangsiri, Sirinapa, Inthachat, Woorawee, Sahasakul, Yuraporn, Aursalung, Amornrat, Wongchang, Pitthaya, Sangkasa-ad, Parichart, Wongpia, Aphinya, Polpanit, Auytin, Nuchuchua, Onanong, Suttisansanee, Uthaiwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738633/
https://www.ncbi.nlm.nih.gov/pubmed/36496713
http://dx.doi.org/10.3390/foods11233905
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author Chupeerach, Chaowanee
Temviriyanukul, Piya
Thangsiri, Sirinapa
Inthachat, Woorawee
Sahasakul, Yuraporn
Aursalung, Amornrat
Wongchang, Pitthaya
Sangkasa-ad, Parichart
Wongpia, Aphinya
Polpanit, Auytin
Nuchuchua, Onanong
Suttisansanee, Uthaiwan
author_facet Chupeerach, Chaowanee
Temviriyanukul, Piya
Thangsiri, Sirinapa
Inthachat, Woorawee
Sahasakul, Yuraporn
Aursalung, Amornrat
Wongchang, Pitthaya
Sangkasa-ad, Parichart
Wongpia, Aphinya
Polpanit, Auytin
Nuchuchua, Onanong
Suttisansanee, Uthaiwan
author_sort Chupeerach, Chaowanee
collection PubMed
description Legumes and pulses are important food components with various phytochemicals and health benefits. However, the health-related bioactivities of some underutilized species remain uninvestigated. To breed a new bean lineage with particular health-related properties, this study investigated phenolics (specifically, isoflavones) and the in vitro inhibitory activities of the enzyme relevant to some non-communicable diseases in underutilized cultivars of Phaseolus lunatus (lima beans), compared to the commonly consumed P. vulgaris (red kidney bean) and beans in the Glycine and Vigna genera. The results indicated that soybeans in the Glycine genus contained the highest isoflavone contents, especially glycitein (1825–2633 mg/100 g bean) and daidzein (1153–6471 mg/100 g bean), leading to potentially higher enzyme inhibitory activities (25–26% inhibition against α-amylase, 54–60% inhibition against α-glucosidase, 42–46% inhibition against dipeptidyl peptidase IV, 12–19% inhibition against acetylcholinesterase and 20–23% inhibition against butyrylcholinesterase) than those from other genera. Interestingly, lima beans with low isoflavone content (up to 2 mg/100 g bean) still possessed high inhibitory activities against lipase (12–21% inhibition) and β-secretase (50–58% inhibition), suggesting that bioactive compounds other than the isoflavones might be responsible for these activities. Isoflavone contents and enzyme inhibitory activities in Vigna beans were diverse, depending on the particular cultivars. The information gained from this study can be used for further investigation of bioactive components and in-depth health properties, as well as for future breeding of a new lineage of bean with specific health potentials.
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spelling pubmed-97386332022-12-11 Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand Chupeerach, Chaowanee Temviriyanukul, Piya Thangsiri, Sirinapa Inthachat, Woorawee Sahasakul, Yuraporn Aursalung, Amornrat Wongchang, Pitthaya Sangkasa-ad, Parichart Wongpia, Aphinya Polpanit, Auytin Nuchuchua, Onanong Suttisansanee, Uthaiwan Foods Article Legumes and pulses are important food components with various phytochemicals and health benefits. However, the health-related bioactivities of some underutilized species remain uninvestigated. To breed a new bean lineage with particular health-related properties, this study investigated phenolics (specifically, isoflavones) and the in vitro inhibitory activities of the enzyme relevant to some non-communicable diseases in underutilized cultivars of Phaseolus lunatus (lima beans), compared to the commonly consumed P. vulgaris (red kidney bean) and beans in the Glycine and Vigna genera. The results indicated that soybeans in the Glycine genus contained the highest isoflavone contents, especially glycitein (1825–2633 mg/100 g bean) and daidzein (1153–6471 mg/100 g bean), leading to potentially higher enzyme inhibitory activities (25–26% inhibition against α-amylase, 54–60% inhibition against α-glucosidase, 42–46% inhibition against dipeptidyl peptidase IV, 12–19% inhibition against acetylcholinesterase and 20–23% inhibition against butyrylcholinesterase) than those from other genera. Interestingly, lima beans with low isoflavone content (up to 2 mg/100 g bean) still possessed high inhibitory activities against lipase (12–21% inhibition) and β-secretase (50–58% inhibition), suggesting that bioactive compounds other than the isoflavones might be responsible for these activities. Isoflavone contents and enzyme inhibitory activities in Vigna beans were diverse, depending on the particular cultivars. The information gained from this study can be used for further investigation of bioactive components and in-depth health properties, as well as for future breeding of a new lineage of bean with specific health potentials. MDPI 2022-12-03 /pmc/articles/PMC9738633/ /pubmed/36496713 http://dx.doi.org/10.3390/foods11233905 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chupeerach, Chaowanee
Temviriyanukul, Piya
Thangsiri, Sirinapa
Inthachat, Woorawee
Sahasakul, Yuraporn
Aursalung, Amornrat
Wongchang, Pitthaya
Sangkasa-ad, Parichart
Wongpia, Aphinya
Polpanit, Auytin
Nuchuchua, Onanong
Suttisansanee, Uthaiwan
Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand
title Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand
title_full Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand
title_fullStr Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand
title_full_unstemmed Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand
title_short Phenolic Profiles and Bioactivities of Ten Original Lineage Beans in Thailand
title_sort phenolic profiles and bioactivities of ten original lineage beans in thailand
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738633/
https://www.ncbi.nlm.nih.gov/pubmed/36496713
http://dx.doi.org/10.3390/foods11233905
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