Cargando…

Locus Coeruleus Neurons’ Firing Pattern Is Regulated by ERG Voltage-Gated K(+) Channels

Locus coeruleus (LC) neurons, with their extensive innervations throughout the brain, control a broad range of physiological processes. Several ion channels have been characterized in LC neurons that control intrinsic membrane properties and excitability. However, ERG (ether-à-go-go–related gene) K(...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hasan, Sonia, Delicata, Francis, Guasti, Leonardo, Duranti, Claudia, Haidar, Fatemah Mousalem, Arcangeli, Annarosa, Imbrici, Paola, Pessia, Mauro, Valentino, Mario, D’Adamo, Maria Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738708/ https://www.ncbi.nlm.nih.gov/pubmed/36499661 http://dx.doi.org/10.3390/ijms232315334

Ejemplares similares

An activator of voltage-gated K(+) channels Kv1.1 as a therapeutic candidate for episodic ataxia type 1
por: Servettini, Ilenio, et al.
Publicado: (2023)

The Interaction between hERG1 and β1 Integrins Modulates hERG1 Current in Different Pathological Cell Models
por: Chioccioli Altadonna, Ginevra, et al.
Publicado: (2022)

Commentary: A channelopathy mutation in the voltage-sensor discloses contributions of a conserved phenylalanine to gating properties of Kv1.1 channels and ataxia
por: Hasan, Sonia, et al.
Publicado: (2018)

Endogenous opioids gate the locus coeruleus pain generator
por: Norris, Makenzie R., et al.
Publicado: (2023)

Locus coeruleus toggles reciprocal prefrontal firing to reinstate fear
por: Giustino, Thomas F., et al.
Publicado: (2019)

Voltage-Dependent Gating of hERG Potassium Channels
por: Cheng, Yen May, et al.
Publicado: (2012)

Kv1.1 Channelopathies: Pathophysiological Mechanisms and Therapeutic Approaches
por: D’Adamo, Maria Cristina, et al.
Publicado: (2020)

Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with PI3K
por: Petroni, Giulia, et al.
Publicado: (2020)

A channelopathy mutation in the voltage-sensor discloses contributions of a conserved phenylalanine to gating properties of Kv1.1 channels and ataxia
por: Hasan, Sonia, et al.
Publicado: (2017)

Correction: Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with PI3K
por: Petroni, Giulia, et al.
Publicado: (2020)

Ion Channel Targeting with Antibodies and Antibody Fragments for Cancer Diagnosis
por: Duranti, Claudia, et al.
Publicado: (2019)

hERG1 Potassium Channels: Novel Biomarkers in Human Solid Cancers
por: Lastraioli, Elena, et al.
Publicado: (2015)

Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging
por: Duranti, Claudia, et al.
Publicado: (2018)

Locus coeruleus complex of the family Delphinidae
por: Sacchini, Simona, et al.
Publicado: (2018)

Locus Coeruleus in Non-Mammalian Vertebrates
por: Wang, Sijia, et al.
Publicado: (2022)

The Locus Coeruleus Noradrenaline System in Delirium
por: Hansen, Niels, et al.
Publicado: (2021)

The locus coeruleus mediates behavioral flexibility
por: McBurney-Lin, Jim, et al.
Publicado: (2022)

A dynamical systems model of the effect of Locus Coeruleus firing on single trial cortical state dynamics
por: Safaai, Houman, et al.
Publicado: (2014)

Voltage Sensor Gating Charge Transfer in a hERG Potassium Channel Model
por: Colenso, Charlotte K., et al.
Publicado: (2014)

Context-dependent relationships between locus coeruleus firing patterns and coordinated neural activity in the anterior cingulate cortex
por: Joshi, Siddhartha, et al.
Publicado: (2022)

Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease
por: Matschke, Lina A., et al.
Publicado: (2022)

Sex Differences in μ-Opioid Receptor Regulation of the Rat Locus Coeruleus and Their Cognitive Consequences
por: Guajardo, Herminio M, et al.
Publicado: (2017)

Synchronization and spontaneous dynamics in the Locus Coeruleus network
por: Medvedev, Georgi S
Publicado: (2011)

A role for locus coeruleus in Parkinson tremor
por: Isaias, Ioannis U., et al.
Publicado: (2012)

The Effects of Locus Coeruleus and Norepinephrine in Methamphetamine Toxicity
por: Ferrucci, Michela, et al.
Publicado: (2013)

Locus coeruleus and dopaminergic consolidation of everyday memory
por: Takeuchi, Tomonori, et al.
Publicado: (2016)

Locus Coeruleus and Dopamine-Dependent Memory Consolidation
por: Yamasaki, Miwako, et al.
Publicado: (2017)

Divergent influences of the locus coeruleus on migraine pathophysiology
por: Vila-Pueyo, Marta, et al.
Publicado: (2019)

The role of the locus coeruleus in the generation of pathological anxiety
por: Morris, Laurel S., et al.
Publicado: (2020)

Locus Coeruleus Modulates Neuroinflammation in Parkinsonism and Dementia
por: Giorgi, Filippo Sean, et al.
Publicado: (2020)

Fast Localization and Sectioning of Mouse Locus Coeruleus
por: Cao, Song, et al.
Publicado: (2020)

Locus coeruleus in memory formation and Alzheimer's disease
por: James, Tony, et al.
Publicado: (2020)

Natural locus coeruleus dynamics during feeding
por: Sciolino, Natale R., et al.
Publicado: (2022)

Properties and modulation of excitatory inputs to the locus coeruleus
por: Barcomb, Kelsey, et al.
Publicado: (2022)

Locus Coeruleus Dysfunction and Trigeminal Mesencephalic Nucleus Degeneration: A Cue for Periodontal Infection Mediated Damage in Alzheimer’s Disease?
por: Pisani, Flavio, et al.
Publicado: (2023)

Locus coeruleus activation during environmental novelty gates cocaine-induced long-term hyperactivity of dopamine neurons
por: Fois, Giulia R., et al.
Publicado: (2022)

Firing activity of locus coeruleus noradrenergic neurons decreases in necdin-deficient mice, an animal model of Prader–Willi syndrome
por: Wu, Rui-Ni, et al.
Publicado: (2020)

Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels
por: Wang, Zhuren, et al.
Publicado: (2013)

Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature
por: Brunetti, Orazio, et al.
Publicado: (2012)

Tuning arousal with optogenetic modulation of locus coeruleus neurons
por: Carter, Matthew E., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_i546mbvrk7kfp8e6v8cppesegf