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Alterations in UPR Signaling by Methylmercury Trigger Neuronal Cell Death in the Mouse Brain

Methylmercury (MeHg), an environmental toxicant, induces neuronal cell death and injures specific areas of the brain. MeHg is known to induce oxidative and endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) pathway has a dual nature in that it regulates and protects cells from an...

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Detalles Bibliográficos
Autores principales:	Nomura, Ryosuke, Takasugi, Nobumasa, Hiraoka, Hideki, Iijima, Yuta, Iwawaki, Takao, Kumagai, Yoshito, Fujimura, Masatake, Uehara, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738736/ https://www.ncbi.nlm.nih.gov/pubmed/36499738 http://dx.doi.org/10.3390/ijms232315412

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