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Caveolin-1 rs1997623 Single Nucleotide Polymorphism Creates a New Binding Site for the Early B-Cell Factor 1 That Instigates Adipose Tissue CAV1 Protein Overexpression

Caveolin-1 (CAV1) is implicated in the pathophysiology of diabetes and obesity. Previously, we demonstrated an association between the CAV1 rs1997623 C > A variant and metabolic syndrome (MetS). Here, we decipher the functional role of rs1997623 in CAV1 gene regulation. A cohort of 38 patients pa...

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Detalles Bibliográficos
Autores principales: Al Madhoun, Ashraf, Haddad, Dania, Nizam, Rasheeba, Miranda, Lavina, Kochumon, Shihab, Thomas, Reeby, Thanaraj, Thangavel Alphonse, Ahmad, Rasheed, Bitar, Milad S., Al-Mulla, Fahd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738758/
https://www.ncbi.nlm.nih.gov/pubmed/36497195
http://dx.doi.org/10.3390/cells11233937

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