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Human β-Defensin 3 Inhibits Porphyromonas Gingivalis Lipopolysaccharide-Induced Oxidative and Inflammatory Responses of Microglia by Suppression of Cathepsins B and L

Recently, the effects of antibacterial peptides are suggested to have therapeutic potential in Alzheimer’s disease. Furthermore, systemic treatment of Porphyromonas gingivalis (Pg) lipopolysaccharide (LPS) induced Alzheimer’s disease-like neuropathological changes in middle-aged mice. Then, we exami...

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Detalles Bibliográficos
Autores principales: Inoue, Erika, Minatozaki, Shiyo, Katsuta, Yui, Nonaka, Saori, Nakanishi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738813/
https://www.ncbi.nlm.nih.gov/pubmed/36499428
http://dx.doi.org/10.3390/ijms232315099