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The STIM1/2-Regulated Calcium Homeostasis Is Impaired in Hippocampal Neurons of the 5xFAD Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common cause of age-related dementia. Neuronal calcium homeostasis impairment may contribute to AD. Here we demonstrated that voltage-gated calcium (VGC) entry and store-operated calcium (SOC) entry regulated by calcium sensors of intracellular calcium stores STI...

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Detalles Bibliográficos
Autores principales: Skobeleva, Ksenia, Shalygin, Alexey, Mikhaylova, Elena, Guzhova, Irina, Ryazantseva, Maria, Kaznacheyeva, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738900/
https://www.ncbi.nlm.nih.gov/pubmed/36499137
http://dx.doi.org/10.3390/ijms232314810