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Development and Validation of a Nomogram for Predicting Risk of Emergency Department Revisits in Chinese Older Patients
OBJECTIVE: The identification of older patients at risk of repeated emergency department (ED) visits is crucial for managing preventable adverse outcomes. This study aims to identify risk factors associated with ED revisits and to develop and validate a nomogram for predicting risk of geriatric ED r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738955/ https://www.ncbi.nlm.nih.gov/pubmed/36510569 http://dx.doi.org/10.2147/RMHP.S391731 |
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author | Fan, Lijun Xue, Hui Wang, Qian Yan, Yuhan Du, Wei |
author_facet | Fan, Lijun Xue, Hui Wang, Qian Yan, Yuhan Du, Wei |
author_sort | Fan, Lijun |
collection | PubMed |
description | OBJECTIVE: The identification of older patients at risk of repeated emergency department (ED) visits is crucial for managing preventable adverse outcomes. This study aims to identify risk factors associated with ED revisits and to develop and validate a nomogram for predicting risk of geriatric ED revisits. METHODS: This was a cohort study comprising 553 older patients, who attended the two tertiary hospitals EDs in China from August 2018 to February 2019 and were prospectively followed for any unplanned revisit within 1 year after discharge. Patients were randomly assigned to a training or validation set at a ratio of 2:1. Stepwise selection procedure was applied to select factors associated with ED revisits for inclusion in a multivariable logistic model from which a nomogram was elaborated. Discrimination, calibration and clinical utility of the nomogram were assessed using C-statistic, calibration plot, Hosmer-Lemeshow test, and decision curve analysis (DCA). RESULTS: The final nomogram included four predictors for ED revisits: age, BMI, frailty and polypharmacy. Older patients having revisits were more likely to be frail (OR = 1.17, p = 0.031), have polypharmacy (OR = 1.69, p = 0.049) or BMI <18.5 kg/m(2) (OR = 2.45, p = 0.025), and were less likely to be older than 90 years (OR = 0.21, p = 0.002). The nomogram demonstrated acceptable discrimination ability in the training (C-index = 0.661) and validation sets (C-index = 0.651), satisfactory calibration (p > 0.05), and good clinical applicability. CONCLUSION: A nomogram incorporating four obtainable variables was constructed to individualize ED readmission risk in older patients. These patients may benefit from early triage and better-targeted care if considering the nomogram as a clinical decision aid. |
format | Online Article Text |
id | pubmed-9738955 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-97389552022-12-11 Development and Validation of a Nomogram for Predicting Risk of Emergency Department Revisits in Chinese Older Patients Fan, Lijun Xue, Hui Wang, Qian Yan, Yuhan Du, Wei Risk Manag Healthc Policy Original Research OBJECTIVE: The identification of older patients at risk of repeated emergency department (ED) visits is crucial for managing preventable adverse outcomes. This study aims to identify risk factors associated with ED revisits and to develop and validate a nomogram for predicting risk of geriatric ED revisits. METHODS: This was a cohort study comprising 553 older patients, who attended the two tertiary hospitals EDs in China from August 2018 to February 2019 and were prospectively followed for any unplanned revisit within 1 year after discharge. Patients were randomly assigned to a training or validation set at a ratio of 2:1. Stepwise selection procedure was applied to select factors associated with ED revisits for inclusion in a multivariable logistic model from which a nomogram was elaborated. Discrimination, calibration and clinical utility of the nomogram were assessed using C-statistic, calibration plot, Hosmer-Lemeshow test, and decision curve analysis (DCA). RESULTS: The final nomogram included four predictors for ED revisits: age, BMI, frailty and polypharmacy. Older patients having revisits were more likely to be frail (OR = 1.17, p = 0.031), have polypharmacy (OR = 1.69, p = 0.049) or BMI <18.5 kg/m(2) (OR = 2.45, p = 0.025), and were less likely to be older than 90 years (OR = 0.21, p = 0.002). The nomogram demonstrated acceptable discrimination ability in the training (C-index = 0.661) and validation sets (C-index = 0.651), satisfactory calibration (p > 0.05), and good clinical applicability. CONCLUSION: A nomogram incorporating four obtainable variables was constructed to individualize ED readmission risk in older patients. These patients may benefit from early triage and better-targeted care if considering the nomogram as a clinical decision aid. Dove 2022-12-06 /pmc/articles/PMC9738955/ /pubmed/36510569 http://dx.doi.org/10.2147/RMHP.S391731 Text en © 2022 Fan et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Fan, Lijun Xue, Hui Wang, Qian Yan, Yuhan Du, Wei Development and Validation of a Nomogram for Predicting Risk of Emergency Department Revisits in Chinese Older Patients |
title | Development and Validation of a Nomogram for Predicting Risk of Emergency Department Revisits in Chinese Older Patients |
title_full | Development and Validation of a Nomogram for Predicting Risk of Emergency Department Revisits in Chinese Older Patients |
title_fullStr | Development and Validation of a Nomogram for Predicting Risk of Emergency Department Revisits in Chinese Older Patients |
title_full_unstemmed | Development and Validation of a Nomogram for Predicting Risk of Emergency Department Revisits in Chinese Older Patients |
title_short | Development and Validation of a Nomogram for Predicting Risk of Emergency Department Revisits in Chinese Older Patients |
title_sort | development and validation of a nomogram for predicting risk of emergency department revisits in chinese older patients |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738955/ https://www.ncbi.nlm.nih.gov/pubmed/36510569 http://dx.doi.org/10.2147/RMHP.S391731 |
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