Cargando…

Constipation Mitigation by Rhubarb Extract in Middle-Aged Adults Is Linked to Gut Microbiome Modulation: A Double-Blind Randomized Placebo-Controlled Trial

Gut microbiota alterations are intimately linked to chronic constipation upon aging. We investigated the role of targeted changes in the gut microbiota composition in the relief of constipation symptoms after rhubarb extract (RE) supplementation in middle-aged volunteers. Subjects (95% women, averag...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neyrinck, Audrey M., Rodriguez, Julie, Taminiau, Bernard, Herpin, Florent, Cani, Patrice D., Daube, Georges, Bindels, Laure B., Delzenne, Nathalie M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738964/ https://www.ncbi.nlm.nih.gov/pubmed/36499011 http://dx.doi.org/10.3390/ijms232314685

Ejemplares similares

Improvement of gastrointestinal discomfort and inflammatory status by a synbiotic in middle-aged adults: a double-blind randomized placebo-controlled trial
por: Neyrinck, Audrey M., et al.
Publicado: (2021)

Spirulina Protects against Hepatic Inflammation in Aging: An Effect Related to the Modulation of the Gut Microbiota?
por: Neyrinck, Audrey M., et al.
Publicado: (2017)

Intestinal Sucrase as a Novel Target Contributing to the Regulation of Glycemia by Prebiotics
por: Neyrinck, Audrey M., et al.
Publicado: (2016)

Chitin–glucan and pomegranate polyphenols improve endothelial dysfunction
por: Neyrinck, Audrey M., et al.
Publicado: (2019)

Prebiotic Effect of Berberine and Curcumin Is Associated with the Improvement of Obesity in Mice
por: Neyrinck, Audrey M., et al.
Publicado: (2021)

Non Digestible Oligosaccharides Modulate the Gut Microbiota to Control the Development of Leukemia and Associated Cachexia in Mice
por: Bindels, Laure B., et al.
Publicado: (2015)

Supplementation with crude rhubarb extract lessens liver inflammation and hepatic lipid accumulation in a model of acute alcohol-induced steato-hepatitis
por: Neyrinck, Audrey M, et al.
Publicado: (2014)

Wheat-derived arabinoxylan oligosaccharides with bifidogenic properties abolishes metabolic disorders induced by western diet in mice
por: Neyrinck, Audrey M., et al.
Publicado: (2018)

The Janus Face of Cereals: Wheat‐Derived Prebiotics Counteract the Detrimental Effect of Gluten on Metabolic Homeostasis in Mice Fed a High‐Fat/High‐Sucrose Diet
por: Olivares, Marta, et al.
Publicado: (2019)

Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome
por: Delzenne, Nathalie M, et al.
Publicado: (2011)

The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice
por: Olivares, Marta, et al.
Publicado: (2018)

Klebsiella oxytoca expands in cancer cachexia and acts as a gut pathobiont contributing to intestinal dysfunction
por: Pötgens, Sarah A., et al.
Publicado: (2018)

Implication of trans-11,trans-13 conjugated linoleic acid in the development of hepatic steatosis
por: Pachikian, Barbara D., et al.
Publicado: (2018)

Fat binding capacity and modulation of the gut microbiota both determine the effect of wheat bran fractions on adiposity
por: Suriano, Francesco, et al.
Publicado: (2017)

Inulin Improves Postprandial Hypertriglyceridemia by Modulating Gene Expression in the Small Intestine
por: Hiel, Sophie, et al.
Publicado: (2018)

Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals
por: Rodriguez, Julie, et al.
Publicado: (2022)

Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women
por: Dewulf, Evelyne M, et al.
Publicado: (2013)

Rhubarb Supplementation Prevents Diet-Induced Obesity and Diabetes in Association with Increased Akkermansia muciniphila in Mice
por: Régnier, Marion, et al.
Publicado: (2020)

Functional Effects of EPS-Producing Bifidobacterium Administration on Energy Metabolic Alterations of Diet-Induced Obese Mice
por: Salazar, Nuria, et al.
Publicado: (2019)

Publisher Correction: Microbiota analysis and transient elastography reveal new extra-hepatic components of liver steatosis and fibrosis in obese patients
por: Lanthier, Nicolas, et al.
Publicado: (2021)

Multi‐compartment metabolomics and metagenomics reveal major hepatic and intestinal disturbances in cancer cachectic mice
por: Pötgens, Sarah A., et al.
Publicado: (2021)

Microbiota analysis and transient elastography reveal new extra-hepatic components of liver steatosis and fibrosis in obese patients
por: Lanthier, Nicolas, et al.
Publicado: (2021)

Underlying beneficial effects of Rhubarb on constipation-induced inflammation, disorder of gut microbiome and metabolism
por: Gao, Han, et al.
Publicado: (2022)

Hepatoprotective Effects of Indole, a Gut Microbial Metabolite, in Leptin-Deficient Obese Mice
por: Knudsen, Christelle, et al.
Publicado: (2021)

Synbiotic approach restores intestinal homeostasis and prolongs survival in leukaemic mice with cachexia
por: Bindels, Laure B, et al.
Publicado: (2016)

Role of the Lower and Upper Intestine in the Production and Absorption of Gut Microbiota-Derived PUFA Metabolites
por: Druart, Céline, et al.
Publicado: (2014)

A dynamic association between myosteatosis and liver stiffness: Results from a prospective interventional study in obese patients
por: Nachit, Maxime, et al.
Publicado: (2021)

Breath volatile metabolome reveals the impact of dietary fibres on the gut microbiota: Proof of concept in healthy volunteers
por: Neyrinck, Audrey M., et al.
Publicado: (2022)

Ffar2 expression regulates leukaemic cell growth in vivo
por: Bindels, Laure B, et al.
Publicado: (2017)

The gut microbiota metabolite indole alleviates liver inflammation in mice
por: Beaumont, Martin, et al.
Publicado: (2018)

A Preventive Prebiotic Supplementation Improves the Sweet Taste Perception in Diet-Induced Obese Mice
por: Bernard, Arnaud, et al.
Publicado: (2019)

Prebiotics supplementation improves the endothelial dysfunction in n-3 PUFA-depleted ApoE(-/-) mice
por: Catry, Emilie, et al.
Publicado: (2014)

Liver alterations are not improved by inulin supplementation in alcohol use disorder patients during alcohol withdrawal: A pilot randomized, double-blind, placebo-controlled study
por: Amadieu, Camille, et al.
Publicado: (2022)

Prebiotic dietary fibre intervention improves fecal markers related to inflammation in obese patients: results from the Food4Gut randomized placebo-controlled trial
por: Neyrinck, Audrey M., et al.
Publicado: (2021)

Curcuma longa Extract Associated with White Pepper Lessens High Fat Diet-Induced Inflammation in Subcutaneous Adipose Tissue
por: Neyrinck, Audrey M., et al.
Publicado: (2013)

Noninvasive monitoring of fibre fermentation in healthy volunteers by analyzing breath volatile metabolites: lessons from the FiberTAG intervention study
por: Neyrinck, Audrey M., et al.
Publicado: (2021)

Inulin increases the beneficial effects of rhubarb supplementation on high-fat high-sugar diet-induced metabolic disorders in mice: impact on energy expenditure, brown adipose tissue activity, and microbiota
por: Régnier, Marion, et al.
Publicado: (2023)

Increased gut permeability in cancer cachexia: mechanisms and clinical relevance
por: Bindels, Laure B., et al.
Publicado: (2018)

Evaluation of the relationship between GPR43 and adiposity in human
por: Dewulf, Evelyne M, et al.
Publicado: (2013)

Prebiotic Effects of Wheat Arabinoxylan Related to the Increase in Bifidobacteria, Roseburia and Bacteroides/Prevotella in Diet-Induced Obese Mice
por: Neyrinck, Audrey M., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_4tu9simk3qogj9jsjf8n8i25u5