Cargando…
Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea
Korea was one of the major consumers of asbestos in the late 1900s, and asbestos-related disease patients have been reported continuously to date, owing to long disease latency. Several studies have been conducted to predict the future incidence of malignant mesothelioma and lung cancer in Korea, bu...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738972/ https://www.ncbi.nlm.nih.gov/pubmed/36498008 http://dx.doi.org/10.3390/ijerph192315934 |
_version_ | 1784847683989536768 |
---|---|
author | Huh, Da-An Chae, Woo-Ri Choi, Yun-Hee Kang, Min-Sung Lee, Yong-Jin Moon, Kyong-Whan |
author_facet | Huh, Da-An Chae, Woo-Ri Choi, Yun-Hee Kang, Min-Sung Lee, Yong-Jin Moon, Kyong-Whan |
author_sort | Huh, Da-An |
collection | PubMed |
description | Korea was one of the major consumers of asbestos in the late 1900s, and asbestos-related disease patients have been reported continuously to date, owing to long disease latency. Several studies have been conducted to predict the future incidence of malignant mesothelioma and lung cancer in Korea, but little is understood about the latency time. Therefore, the aim of this study is to estimate the latency period of malignant mesothelioma and asbestos-related lung cancer in Korea and its determinants. We obtained information from the Environmental Health Centers for Asbestos in Korea on the history of asbestos exposure and demographic characteristics of 1933 patients with malignant mesothelioma and asbestos-related lung cancer. In our study, the latency periods for malignant mesothelioma and lung cancer were 33.7 and 40.1 years, respectively. Regardless of the disease type, those with a history of exposure related to the production of asbestos-containing products or asbestos factories had the shortest latency period. In addition, we observed that those who worked in or lived near asbestos mines tended to have a relatively long disease latency. Smoking was associated with shorter latency, but no linear relationship between the lifetime smoking amount (expressed in pack years) and latent time was observed. In addition, the age of initial exposure showed a negative linear association with the latency period for mesothelioma and lung cancer. |
format | Online Article Text |
id | pubmed-9738972 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97389722022-12-11 Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea Huh, Da-An Chae, Woo-Ri Choi, Yun-Hee Kang, Min-Sung Lee, Yong-Jin Moon, Kyong-Whan Int J Environ Res Public Health Article Korea was one of the major consumers of asbestos in the late 1900s, and asbestos-related disease patients have been reported continuously to date, owing to long disease latency. Several studies have been conducted to predict the future incidence of malignant mesothelioma and lung cancer in Korea, but little is understood about the latency time. Therefore, the aim of this study is to estimate the latency period of malignant mesothelioma and asbestos-related lung cancer in Korea and its determinants. We obtained information from the Environmental Health Centers for Asbestos in Korea on the history of asbestos exposure and demographic characteristics of 1933 patients with malignant mesothelioma and asbestos-related lung cancer. In our study, the latency periods for malignant mesothelioma and lung cancer were 33.7 and 40.1 years, respectively. Regardless of the disease type, those with a history of exposure related to the production of asbestos-containing products or asbestos factories had the shortest latency period. In addition, we observed that those who worked in or lived near asbestos mines tended to have a relatively long disease latency. Smoking was associated with shorter latency, but no linear relationship between the lifetime smoking amount (expressed in pack years) and latent time was observed. In addition, the age of initial exposure showed a negative linear association with the latency period for mesothelioma and lung cancer. MDPI 2022-11-29 /pmc/articles/PMC9738972/ /pubmed/36498008 http://dx.doi.org/10.3390/ijerph192315934 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Huh, Da-An Chae, Woo-Ri Choi, Yun-Hee Kang, Min-Sung Lee, Yong-Jin Moon, Kyong-Whan Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea |
title | Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea |
title_full | Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea |
title_fullStr | Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea |
title_full_unstemmed | Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea |
title_short | Disease Latency according to Asbestos Exposure Characteristics among Malignant Mesothelioma and Asbestos-Related Lung Cancer Cases in South Korea |
title_sort | disease latency according to asbestos exposure characteristics among malignant mesothelioma and asbestos-related lung cancer cases in south korea |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738972/ https://www.ncbi.nlm.nih.gov/pubmed/36498008 http://dx.doi.org/10.3390/ijerph192315934 |
work_keys_str_mv | AT huhdaan diseaselatencyaccordingtoasbestosexposurecharacteristicsamongmalignantmesotheliomaandasbestosrelatedlungcancercasesinsouthkorea AT chaewoori diseaselatencyaccordingtoasbestosexposurecharacteristicsamongmalignantmesotheliomaandasbestosrelatedlungcancercasesinsouthkorea AT choiyunhee diseaselatencyaccordingtoasbestosexposurecharacteristicsamongmalignantmesotheliomaandasbestosrelatedlungcancercasesinsouthkorea AT kangminsung diseaselatencyaccordingtoasbestosexposurecharacteristicsamongmalignantmesotheliomaandasbestosrelatedlungcancercasesinsouthkorea AT leeyongjin diseaselatencyaccordingtoasbestosexposurecharacteristicsamongmalignantmesotheliomaandasbestosrelatedlungcancercasesinsouthkorea AT moonkyongwhan diseaselatencyaccordingtoasbestosexposurecharacteristicsamongmalignantmesotheliomaandasbestosrelatedlungcancercasesinsouthkorea |