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miR-31-5p Regulates Type I Interferon by Targeting SLC15A4 in Plasmacytoid Dendritic Cells of Systemic Lupus Erythematosus

BACKGROUND: Plasmacytoid dendritic cells (pDCs) are the main producers of type I interferon (IFN-I), and the excessive production of IFN-I is a hallmark of systemic lupus erythematosus (SLE). Both SLC15A4 and miR-31-5p are SLE susceptibility-related genes, and SLC15A4 has been implicated an importan...

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Detalles Bibliográficos
Autores principales:	Li, Shifei, Wu, Qijun, Jiang, Zhuyan, Wu, Yaguang, Li, Yuhong, Ni, Bing, Xiao, Jun, Zhai, Zhifang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739073/ https://www.ncbi.nlm.nih.gov/pubmed/36510495 http://dx.doi.org/10.2147/JIR.S383623

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