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Glucose and Cell Context-Dependent Impact of BMI-1 Inhibitor PTC-209 on AKT Pathway in Endometrial Cancer Cells
SIMPLE SUMMARY: The insulin/IGF-1/AKT pathway is a key event linking metabolic syndrome with endometrial cancer. It has been found that BMI-1 may also influence the AKT kinase pathway and that increased activity is associated with cancer onset and progression. The aim of our study was to determine t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739103/ https://www.ncbi.nlm.nih.gov/pubmed/36497428 http://dx.doi.org/10.3390/cancers14235947 |