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Glucose and Cell Context-Dependent Impact of BMI-1 Inhibitor PTC-209 on AKT Pathway in Endometrial Cancer Cells

SIMPLE SUMMARY: The insulin/IGF-1/AKT pathway is a key event linking metabolic syndrome with endometrial cancer. It has been found that BMI-1 may also influence the AKT kinase pathway and that increased activity is associated with cancer onset and progression. The aim of our study was to determine t...

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Detalles Bibliográficos
Autores principales: Zaczek, Agnieszka, Szustka, Aleksandra, Krześlak, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739103/
https://www.ncbi.nlm.nih.gov/pubmed/36497428
http://dx.doi.org/10.3390/cancers14235947

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