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Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study

(1) Background: Respiratory disease is a leading cause of morbidity, mortality, and poor quality of life in children with cerebral palsy (CP). This study describes the prevalence of CP-related respiratory disease and the non-modifiable risk factors for respiratory-related hospital admissions in the...

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Autores principales: Sorhage, Alexandra, Keenan, Samantha, Chong, Jimmy, Byrnes, Cass, Blackmore, Amanda Marie, Mackey, Anna, Hill, Timothy, Han, Dug Yeo, Stott, Ngaire Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739165/
https://www.ncbi.nlm.nih.gov/pubmed/36498542
http://dx.doi.org/10.3390/jcm11236968
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author Sorhage, Alexandra
Keenan, Samantha
Chong, Jimmy
Byrnes, Cass
Blackmore, Amanda Marie
Mackey, Anna
Hill, Timothy
Han, Dug Yeo
Stott, Ngaire Susan
author_facet Sorhage, Alexandra
Keenan, Samantha
Chong, Jimmy
Byrnes, Cass
Blackmore, Amanda Marie
Mackey, Anna
Hill, Timothy
Han, Dug Yeo
Stott, Ngaire Susan
author_sort Sorhage, Alexandra
collection PubMed
description (1) Background: Respiratory disease is a leading cause of morbidity, mortality, and poor quality of life in children with cerebral palsy (CP). This study describes the prevalence of CP-related respiratory disease and the non-modifiable risk factors for respiratory-related hospital admissions in the Aotearoa New Zealand population. (2) Methods: New Zealand Cerebral Palsy Register (NZCPR) participant data and de-identified data from the National Minimum Dataset and Pharmaceutical Dispensing Collections were linked to identify all respiratory-related hospital admissions and respiratory illness-related antibiotic exposure over 5 years in individuals with CP (0–26 years). (3) Results: Risk factors for respiratory-related hospital admissions included being classified Gross Motor Function Classification System (GMFCS) IV or V compared to GMFCS I [OR = 4.37 (2.90–6.58), p < 0.0001; OR = 11.8 (7.69–18.10), p < 0.0001, respectively,]; having ≥2 antibiotics dispensed per year [OR = 4.42 (3.01–6.48), p < 0.0001]; and being of Māori ethnicity [OR = 1.47 (1.13–1.93), p < 0.0047]. Māori experienced health inequities compared to non-Māori, with greater functional disability, and also experienced greater antibiotic dispensing than the general population. (4) Conclusion: Māori children and young adults have a higher risk of respiratory-related illness. Priority should be given to the screening for potentially modifiable risk factors for all children with CP from diagnosis onwards in a way that ensures Māori health equity.
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spelling pubmed-97391652022-12-11 Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study Sorhage, Alexandra Keenan, Samantha Chong, Jimmy Byrnes, Cass Blackmore, Amanda Marie Mackey, Anna Hill, Timothy Han, Dug Yeo Stott, Ngaire Susan J Clin Med Article (1) Background: Respiratory disease is a leading cause of morbidity, mortality, and poor quality of life in children with cerebral palsy (CP). This study describes the prevalence of CP-related respiratory disease and the non-modifiable risk factors for respiratory-related hospital admissions in the Aotearoa New Zealand population. (2) Methods: New Zealand Cerebral Palsy Register (NZCPR) participant data and de-identified data from the National Minimum Dataset and Pharmaceutical Dispensing Collections were linked to identify all respiratory-related hospital admissions and respiratory illness-related antibiotic exposure over 5 years in individuals with CP (0–26 years). (3) Results: Risk factors for respiratory-related hospital admissions included being classified Gross Motor Function Classification System (GMFCS) IV or V compared to GMFCS I [OR = 4.37 (2.90–6.58), p < 0.0001; OR = 11.8 (7.69–18.10), p < 0.0001, respectively,]; having ≥2 antibiotics dispensed per year [OR = 4.42 (3.01–6.48), p < 0.0001]; and being of Māori ethnicity [OR = 1.47 (1.13–1.93), p < 0.0047]. Māori experienced health inequities compared to non-Māori, with greater functional disability, and also experienced greater antibiotic dispensing than the general population. (4) Conclusion: Māori children and young adults have a higher risk of respiratory-related illness. Priority should be given to the screening for potentially modifiable risk factors for all children with CP from diagnosis onwards in a way that ensures Māori health equity. MDPI 2022-11-25 /pmc/articles/PMC9739165/ /pubmed/36498542 http://dx.doi.org/10.3390/jcm11236968 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sorhage, Alexandra
Keenan, Samantha
Chong, Jimmy
Byrnes, Cass
Blackmore, Amanda Marie
Mackey, Anna
Hill, Timothy
Han, Dug Yeo
Stott, Ngaire Susan
Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study
title Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study
title_full Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study
title_fullStr Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study
title_full_unstemmed Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study
title_short Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study
title_sort respiratory health inequities among children and young adults with cerebral palsy in aotearoa new zealand: a data linkage study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739165/
https://www.ncbi.nlm.nih.gov/pubmed/36498542
http://dx.doi.org/10.3390/jcm11236968
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