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Effects of Corchorusoside C on NF-κB and PARP-1 Molecular Targets and Toxicity Profile in Zebrafish

The present study aims to continue the study of corchorusoside C (1), a cardenolide isolated from Streptocaulon juventas, as a potential anticancer agent. A mechanistic study was pursued in a zebrafish model and in DU-145 prostate cancer cells to investigate the selectivity of 1 towards NF-κB and PA...

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Detalles Bibliográficos
Autores principales: Mirtallo Ezzone, Nathan P., Anaya-Eugenio, Gerardo D., Addo, Ermias Mekuria, Ren, Yulin, Kinghorn, A. Douglas, Carcache de Blanco, Esperanza J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739208/
https://www.ncbi.nlm.nih.gov/pubmed/36498874
http://dx.doi.org/10.3390/ijms232314546