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Effects of Corchorusoside C on NF-κB and PARP-1 Molecular Targets and Toxicity Profile in Zebrafish
The present study aims to continue the study of corchorusoside C (1), a cardenolide isolated from Streptocaulon juventas, as a potential anticancer agent. A mechanistic study was pursued in a zebrafish model and in DU-145 prostate cancer cells to investigate the selectivity of 1 towards NF-κB and PA...
Autores principales: | Mirtallo Ezzone, Nathan P., Anaya-Eugenio, Gerardo D., Addo, Ermias Mekuria, Ren, Yulin, Kinghorn, A. Douglas, Carcache de Blanco, Esperanza J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739208/ https://www.ncbi.nlm.nih.gov/pubmed/36498874 http://dx.doi.org/10.3390/ijms232314546 |
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