Cargando…
Analysis of Circulating C19MC MicroRNA as an Early Marker of Hypertension and Preeclampsia in Pregnant Patients: A Systematic Review
Preeclampsia and hypertension complicate several pregnancies. Identifying women at risk of developing these conditions is essential to establish potential treatment modalities. Biomarkers such as C19MC microRNA in pregnant patients wopuld assist in defining pregnancy surveillance and implementing in...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739231/ https://www.ncbi.nlm.nih.gov/pubmed/36498625 http://dx.doi.org/10.3390/jcm11237051 |
_version_ | 1784847754102571008 |
---|---|
author | Kondracka, Adrianna Jaszczuk, Ilona Koczkodaj, Dorota Kondracki, Bartosz Frąszczak, Karolina Oniszczuk, Anna Rybak-Krzyszkowska, Magda Staniczek, Jakub Filip, Agata Kwaśniewska, Anna |
author_facet | Kondracka, Adrianna Jaszczuk, Ilona Koczkodaj, Dorota Kondracki, Bartosz Frąszczak, Karolina Oniszczuk, Anna Rybak-Krzyszkowska, Magda Staniczek, Jakub Filip, Agata Kwaśniewska, Anna |
author_sort | Kondracka, Adrianna |
collection | PubMed |
description | Preeclampsia and hypertension complicate several pregnancies. Identifying women at risk of developing these conditions is essential to establish potential treatment modalities. Biomarkers such as C19MC microRNA in pregnant patients wopuld assist in defining pregnancy surveillance and implementing interventions. This study sought to analyze circulating C19MC microRNA as an early marker of hypertension and preeclampsia in pregnant patients. A systematic review was undertaken using the following registers: disease registries, pregnancy registries, and pregnancy exposure registries, and the following databases: PubMed, CINAHL, Web of Science, Scopus, and EMBASE. The risk of bias was assessed using the Cochrane technique. From the 45 publications retrieved from the registers and databases, only 21 were included in the review after the removal of duplicates, screening, and eligibility evaluation. All 210 publications had a low risk of bias and illuminated the potential use of circulating C19MC microRNA as an early marker of hypertension and preeclampsia in pregnant patients. Therefore, it was concluded that C19MC microRNA can be used as an early marker of gestational preeclampsia and hypertension. |
format | Online Article Text |
id | pubmed-9739231 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97392312022-12-11 Analysis of Circulating C19MC MicroRNA as an Early Marker of Hypertension and Preeclampsia in Pregnant Patients: A Systematic Review Kondracka, Adrianna Jaszczuk, Ilona Koczkodaj, Dorota Kondracki, Bartosz Frąszczak, Karolina Oniszczuk, Anna Rybak-Krzyszkowska, Magda Staniczek, Jakub Filip, Agata Kwaśniewska, Anna J Clin Med Systematic Review Preeclampsia and hypertension complicate several pregnancies. Identifying women at risk of developing these conditions is essential to establish potential treatment modalities. Biomarkers such as C19MC microRNA in pregnant patients wopuld assist in defining pregnancy surveillance and implementing interventions. This study sought to analyze circulating C19MC microRNA as an early marker of hypertension and preeclampsia in pregnant patients. A systematic review was undertaken using the following registers: disease registries, pregnancy registries, and pregnancy exposure registries, and the following databases: PubMed, CINAHL, Web of Science, Scopus, and EMBASE. The risk of bias was assessed using the Cochrane technique. From the 45 publications retrieved from the registers and databases, only 21 were included in the review after the removal of duplicates, screening, and eligibility evaluation. All 210 publications had a low risk of bias and illuminated the potential use of circulating C19MC microRNA as an early marker of hypertension and preeclampsia in pregnant patients. Therefore, it was concluded that C19MC microRNA can be used as an early marker of gestational preeclampsia and hypertension. MDPI 2022-11-29 /pmc/articles/PMC9739231/ /pubmed/36498625 http://dx.doi.org/10.3390/jcm11237051 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Kondracka, Adrianna Jaszczuk, Ilona Koczkodaj, Dorota Kondracki, Bartosz Frąszczak, Karolina Oniszczuk, Anna Rybak-Krzyszkowska, Magda Staniczek, Jakub Filip, Agata Kwaśniewska, Anna Analysis of Circulating C19MC MicroRNA as an Early Marker of Hypertension and Preeclampsia in Pregnant Patients: A Systematic Review |
title | Analysis of Circulating C19MC MicroRNA as an Early Marker of Hypertension and Preeclampsia in Pregnant Patients: A Systematic Review |
title_full | Analysis of Circulating C19MC MicroRNA as an Early Marker of Hypertension and Preeclampsia in Pregnant Patients: A Systematic Review |
title_fullStr | Analysis of Circulating C19MC MicroRNA as an Early Marker of Hypertension and Preeclampsia in Pregnant Patients: A Systematic Review |
title_full_unstemmed | Analysis of Circulating C19MC MicroRNA as an Early Marker of Hypertension and Preeclampsia in Pregnant Patients: A Systematic Review |
title_short | Analysis of Circulating C19MC MicroRNA as an Early Marker of Hypertension and Preeclampsia in Pregnant Patients: A Systematic Review |
title_sort | analysis of circulating c19mc microrna as an early marker of hypertension and preeclampsia in pregnant patients: a systematic review |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739231/ https://www.ncbi.nlm.nih.gov/pubmed/36498625 http://dx.doi.org/10.3390/jcm11237051 |
work_keys_str_mv | AT kondrackaadrianna analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT jaszczukilona analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT koczkodajdorota analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT kondrackibartosz analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT fraszczakkarolina analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT oniszczukanna analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT rybakkrzyszkowskamagda analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT staniczekjakub analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT filipagata analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview AT kwasniewskaanna analysisofcirculatingc19mcmicrornaasanearlymarkerofhypertensionandpreeclampsiainpregnantpatientsasystematicreview |