Cargando…

The Potential Role of R4 Regulators of G Protein Signaling (RGS) Proteins in Type 2 Diabetes Mellitus

Type 2 diabetes mellitus (T2DM) is a complex and heterogeneous disease that primarily results from impaired insulin secretion or insulin resistance (IR). G protein-coupled receptors (GPCRs) are proposed as therapeutic targets for T2DM. GPCRs transduce signals via the Gα protein, playing an integral...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiaohong, Lv, Hongyan, Mei, Juan, Ji, Bingyuan, Huang, Shuhong, Li, Xuezhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739376/ https://www.ncbi.nlm.nih.gov/pubmed/36497154 http://dx.doi.org/10.3390/cells11233897

Ejemplares similares

Characteristics of a Regulator of G-Protein Signaling (RGS) rgsC in Aspergillus fumigatus
por: Kim, Young, et al.
Publicado: (2017)

A Global Map of G Protein Signaling Regulation by RGS Proteins
por: Masuho, Ikuo, et al.
Publicado: (2020)

Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells
por: Hooks, Shelley B, et al.
Publicado: (2010)

Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management
por: Senese, Nicolas B., et al.
Publicado: (2020)

Endocytosis of Seven-Transmembrane RGS Protein Activates G- protein Coupled Signaling in Arabidopsis
por: Urano, Daisuke, et al.
Publicado: (2012)

The Repertoire of Heterotrimeric G Proteins and RGS Proteins in Ciona intestinalis
por: Prasobh, R., et al.
Publicado: (2009)

Regulator of G Protein Signaling 2 (RGS2) and RGS4 Form Distinct G Protein-Dependent Complexes with Protease Activated-Receptor 1 (PAR1) in Live Cells
por: Ghil, Sungho, et al.
Publicado: (2014)

Regulator of G-Protein Signaling – 5 (RGS5) Is a Novel Repressor of Hedgehog Signaling
por: Mahoney, William M., et al.
Publicado: (2013)

Gβ5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling
por: Xie, Keqiang, et al.
Publicado: (2010)

Regulators of G-protein signaling, RGS2 and RGS4, inhibit protease-activated receptor 4-mediated signaling by forming a complex with the receptor and Gα in live cells
por: Kim, Yukeyoung, et al.
Publicado: (2020)

Duplicated RGS (Regulator of G-protein signaling) proteins exhibit conserved biochemical but differential transcriptional regulation of heterotrimeric G-protein signaling in Brassica species
por: Kumar, Roshan, et al.
Publicado: (2018)

Regulator of G-Protein Signaling 14 (RGS14) Is a Selective H-Ras Effector
por: Willard, Francis S., et al.
Publicado: (2009)

G-Protein Signaling Protein-17 (RGS17) Is Upregulated and Promotes Tumor Growth and Migration in Human Colorectal Carcinoma
por: Li, Ling, et al.
Publicado: (2018)

GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes
por: Orlandi, Cesare, et al.
Publicado: (2012)

RGS Proteins in Heart: Brakes on the Vagus
por: Stewart, Adele, et al.
Publicado: (2012)

Eight RGS and RGS-like Proteins Orchestrate Growth, Differentiation, and Pathogenicity of Magnaporthe oryzae
por: Zhang, Haifeng, et al.
Publicado: (2011)

Cardiac RGS Proteins in Human Heart Failure and Atrial Fibrillation: Focus on RGS4
por: Borges, Jordana I., et al.
Publicado: (2023)

Integrating energy calculations with functional assays to decipher the specificity of G-protein inactivation by RGS proteins
por: Kosloff, Mickey, et al.
Publicado: (2011)

Chemical Genetics Reveals an RGS/G-Protein Role in the Action of a Compound
por: Fitzgerald, Kevin, et al.
Publicado: (2006)

Feeding and fasting controls liver expression of a regulator of G protein signaling (Rgs16) in periportal hepatocytes
por: Huang, Jie, et al.
Publicado: (2006)

Interferonβ-1b Induces the Expression of RGS1 a Negative Regulator of G-Protein Signaling
por: Tran, Tiffany, et al.
Publicado: (2010)

Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses
por: Zhang, Huiping, et al.
Publicado: (2012)

A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation
por: Schroer, Adam B., et al.
Publicado: (2019)

Analysis of regulator of G-protein signalling 2 (RGS2) expression and function during prostate cancer progression
por: Linder, Anna, et al.
Publicado: (2018)

Regulator of G Protein Signalling 4 (RGS4) as a Novel Target for the Treatment of Sensorineural Hearing Loss
por: Fok, Christine, et al.
Publicado: (2020)

Conditional disruption of interactions between Gα(i2) and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury
por: Parra, Sergio, et al.
Publicado: (2014)

The regulator of G protein signaling (RGS) domain of G protein–coupled receptor kinase 5 (GRK5) regulates plasma membrane localization and function
por: Xu, Hua, et al.
Publicado: (2014)

Correction: Eight RGS and RGS-like Proteins Orchestrate Growth, Differentiation, and Pathogenicity of Magnaporthe oryzae
por: Zhang, Haifeng, et al.
Publicado: (2019)

Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex
por: Patil, Dipak N, et al.
Publicado: (2018)

RGS proteins and their roles in cancer: friend or foe?
por: Li, Lin, et al.
Publicado: (2023)

Seven-transmembrane receptor protein RgsP and cell wall-binding protein RgsM promote unipolar growth in Rhizobiales
por: Schäper, Simon, et al.
Publicado: (2018)

The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets
por: Vivot, Kevin, et al.
Publicado: (2016)

Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor’s proangiogenic microenvironment
por: Silini, Antonietta, et al.
Publicado: (2011)

Genome-wide screening for the G-protein-coupled receptor (GPCR) pathway-related therapeutic gene RGS19 (regulator of G protein signaling 19) in bladder cancer
por: Liu, Yue, et al.
Publicado: (2021)

JA-Induced Endocytosis of AtRGS1 Is Involved in G-Protein Mediated JA Responses
por: Li, Li, et al.
Publicado: (2019)

Filling in the gaps: SNX-RGS proteins as multiorganelle tethers
por: Hariri, Hanaa, et al.
Publicado: (2022)

Regulator of G-Protein Signalling-14 (RGS14) Regulates the Activation of αMβ2 Integrin during Phagocytosis
por: Lim, Jenson, et al.
Publicado: (2013)

Critical Role of Regulator G-Protein Signaling 10 (RGS10) in Modulating Macrophage M1/M2 Activation
por: Lee, Jae-Kyung, et al.
Publicado: (2013)

Adenosine Receptors Differentially Regulate the Expression of Regulators of G-Protein Signalling (RGS) 2, 3 and 4 in Astrocyte-Like Cells
por: Eusemann, Till Nicolas, et al.
Publicado: (2015)

Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II–mediated blood pressure control
por: Patel, Jyoti, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_j5a27qlgh5s4et6dcel06celvb