The Spectrum of Pharmacological Actions of Syringetin and Its Natural Derivatives—A Summary Review

Mono- and poly-O-methylated flavonols and their glycoside derivatives belong to the group of natural plant polyphenols with a wide spectrum of pharmacological activities. These compounds are known for their antioxidant, antimutagenic, hepatoprotective, antidiabetic, and antilipogenic properties. Add...

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Autores principales: Chmiel, Marcelina, Stompor-Gorący, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739508/
https://www.ncbi.nlm.nih.gov/pubmed/36501187
http://dx.doi.org/10.3390/nu14235157
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author Chmiel, Marcelina
Stompor-Gorący, Monika
author_facet Chmiel, Marcelina
Stompor-Gorący, Monika
author_sort Chmiel, Marcelina
collection PubMed
description Mono- and poly-O-methylated flavonols and their glycoside derivatives belong to the group of natural plant polyphenols with a wide spectrum of pharmacological activities. These compounds are known for their antioxidant, antimutagenic, hepatoprotective, antidiabetic, and antilipogenic properties. Additionally, they inhibit carcinogenesis and cancer development. Having in mind the multidirectional biological activity of methylated flavonols, we would like to support further study on their health-promoting activities; in this review we summarized the most recent reports on syringetin and some of its structural analogues: laricitrin, ayanin, and isorhamnetin. Natural sources and biological potential of these substances were described based on the latest research papers.
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spelling pubmed-97395082022-12-11 The Spectrum of Pharmacological Actions of Syringetin and Its Natural Derivatives—A Summary Review Chmiel, Marcelina Stompor-Gorący, Monika Nutrients Review Mono- and poly-O-methylated flavonols and their glycoside derivatives belong to the group of natural plant polyphenols with a wide spectrum of pharmacological activities. These compounds are known for their antioxidant, antimutagenic, hepatoprotective, antidiabetic, and antilipogenic properties. Additionally, they inhibit carcinogenesis and cancer development. Having in mind the multidirectional biological activity of methylated flavonols, we would like to support further study on their health-promoting activities; in this review we summarized the most recent reports on syringetin and some of its structural analogues: laricitrin, ayanin, and isorhamnetin. Natural sources and biological potential of these substances were described based on the latest research papers. MDPI 2022-12-04 /pmc/articles/PMC9739508/ /pubmed/36501187 http://dx.doi.org/10.3390/nu14235157 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chmiel, Marcelina
Stompor-Gorący, Monika
The Spectrum of Pharmacological Actions of Syringetin and Its Natural Derivatives—A Summary Review
title The Spectrum of Pharmacological Actions of Syringetin and Its Natural Derivatives—A Summary Review
title_full The Spectrum of Pharmacological Actions of Syringetin and Its Natural Derivatives—A Summary Review
title_fullStr The Spectrum of Pharmacological Actions of Syringetin and Its Natural Derivatives—A Summary Review
title_full_unstemmed The Spectrum of Pharmacological Actions of Syringetin and Its Natural Derivatives—A Summary Review
title_short The Spectrum of Pharmacological Actions of Syringetin and Its Natural Derivatives—A Summary Review
title_sort spectrum of pharmacological actions of syringetin and its natural derivatives—a summary review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739508/
https://www.ncbi.nlm.nih.gov/pubmed/36501187
http://dx.doi.org/10.3390/nu14235157
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