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Asbestos Exposure and Severity of COVID-19

Background: The aim of this study was to analyse the relationship between occupational exposure to asbestos and the severity of SARS-CoV-2 infection. Methods: We evaluated patients who survived admission in our centre for COVID-19 pneumonia. Demographic, analytical, and clinical variables were colle...

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Autores principales: Granados, Galo, Sáez-López, María, Aljama, Cristina, Sampol, Júlia, Cruz, María-Jesús, Ferrer, Jaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739528/
https://www.ncbi.nlm.nih.gov/pubmed/36498378
http://dx.doi.org/10.3390/ijerph192316305
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author Granados, Galo
Sáez-López, María
Aljama, Cristina
Sampol, Júlia
Cruz, María-Jesús
Ferrer, Jaume
author_facet Granados, Galo
Sáez-López, María
Aljama, Cristina
Sampol, Júlia
Cruz, María-Jesús
Ferrer, Jaume
author_sort Granados, Galo
collection PubMed
description Background: The aim of this study was to analyse the relationship between occupational exposure to asbestos and the severity of SARS-CoV-2 infection. Methods: We evaluated patients who survived admission in our centre for COVID-19 pneumonia. Demographic, analytical, and clinical variables were collected during admission. After discharge, a previously validated occupational exposure to asbestos questionnaire was administered. Spirometry, CO diffusion test, the 6-min walk test, and high-resolution chest CT were performed. Patients who required respiratory support (oxygen, CPAP, or NIV) were considered severe. Results: In total, 293 patients (mean age 54 + 13 years) were included. Occupational exposure to asbestos was detected in 67 (24%). Patients with occupational exposure to asbestos had a higher frequency of COVID-19 pneumonia requiring respiratory support (n = 52, 77.6%) than their unexposed peers (n = 139, 61.5%) (p = 0.015). Asbestos exposure was associated with COVID-19 severity in the univariate but not in the multivariate analysis. No differences were found regarding follow-up variables including spirometry and the DLCO diffusion, the 6-min walk test, and CT alterations. Conclusions: In hospitalised patients with COVID-19 pneumonia, those with occupational exposure to asbestos more frequently needed respiratory support. However, an independent association between asbestos exposure and COVID-19 severity could not be confirmed.
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spelling pubmed-97395282022-12-11 Asbestos Exposure and Severity of COVID-19 Granados, Galo Sáez-López, María Aljama, Cristina Sampol, Júlia Cruz, María-Jesús Ferrer, Jaume Int J Environ Res Public Health Article Background: The aim of this study was to analyse the relationship between occupational exposure to asbestos and the severity of SARS-CoV-2 infection. Methods: We evaluated patients who survived admission in our centre for COVID-19 pneumonia. Demographic, analytical, and clinical variables were collected during admission. After discharge, a previously validated occupational exposure to asbestos questionnaire was administered. Spirometry, CO diffusion test, the 6-min walk test, and high-resolution chest CT were performed. Patients who required respiratory support (oxygen, CPAP, or NIV) were considered severe. Results: In total, 293 patients (mean age 54 + 13 years) were included. Occupational exposure to asbestos was detected in 67 (24%). Patients with occupational exposure to asbestos had a higher frequency of COVID-19 pneumonia requiring respiratory support (n = 52, 77.6%) than their unexposed peers (n = 139, 61.5%) (p = 0.015). Asbestos exposure was associated with COVID-19 severity in the univariate but not in the multivariate analysis. No differences were found regarding follow-up variables including spirometry and the DLCO diffusion, the 6-min walk test, and CT alterations. Conclusions: In hospitalised patients with COVID-19 pneumonia, those with occupational exposure to asbestos more frequently needed respiratory support. However, an independent association between asbestos exposure and COVID-19 severity could not be confirmed. MDPI 2022-12-06 /pmc/articles/PMC9739528/ /pubmed/36498378 http://dx.doi.org/10.3390/ijerph192316305 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Granados, Galo
Sáez-López, María
Aljama, Cristina
Sampol, Júlia
Cruz, María-Jesús
Ferrer, Jaume
Asbestos Exposure and Severity of COVID-19
title Asbestos Exposure and Severity of COVID-19
title_full Asbestos Exposure and Severity of COVID-19
title_fullStr Asbestos Exposure and Severity of COVID-19
title_full_unstemmed Asbestos Exposure and Severity of COVID-19
title_short Asbestos Exposure and Severity of COVID-19
title_sort asbestos exposure and severity of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739528/
https://www.ncbi.nlm.nih.gov/pubmed/36498378
http://dx.doi.org/10.3390/ijerph192316305
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