Cargando…
Asbestos Exposure and Severity of COVID-19
Background: The aim of this study was to analyse the relationship between occupational exposure to asbestos and the severity of SARS-CoV-2 infection. Methods: We evaluated patients who survived admission in our centre for COVID-19 pneumonia. Demographic, analytical, and clinical variables were colle...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739528/ https://www.ncbi.nlm.nih.gov/pubmed/36498378 http://dx.doi.org/10.3390/ijerph192316305 |
_version_ | 1784847828988723200 |
---|---|
author | Granados, Galo Sáez-López, María Aljama, Cristina Sampol, Júlia Cruz, María-Jesús Ferrer, Jaume |
author_facet | Granados, Galo Sáez-López, María Aljama, Cristina Sampol, Júlia Cruz, María-Jesús Ferrer, Jaume |
author_sort | Granados, Galo |
collection | PubMed |
description | Background: The aim of this study was to analyse the relationship between occupational exposure to asbestos and the severity of SARS-CoV-2 infection. Methods: We evaluated patients who survived admission in our centre for COVID-19 pneumonia. Demographic, analytical, and clinical variables were collected during admission. After discharge, a previously validated occupational exposure to asbestos questionnaire was administered. Spirometry, CO diffusion test, the 6-min walk test, and high-resolution chest CT were performed. Patients who required respiratory support (oxygen, CPAP, or NIV) were considered severe. Results: In total, 293 patients (mean age 54 + 13 years) were included. Occupational exposure to asbestos was detected in 67 (24%). Patients with occupational exposure to asbestos had a higher frequency of COVID-19 pneumonia requiring respiratory support (n = 52, 77.6%) than their unexposed peers (n = 139, 61.5%) (p = 0.015). Asbestos exposure was associated with COVID-19 severity in the univariate but not in the multivariate analysis. No differences were found regarding follow-up variables including spirometry and the DLCO diffusion, the 6-min walk test, and CT alterations. Conclusions: In hospitalised patients with COVID-19 pneumonia, those with occupational exposure to asbestos more frequently needed respiratory support. However, an independent association between asbestos exposure and COVID-19 severity could not be confirmed. |
format | Online Article Text |
id | pubmed-9739528 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97395282022-12-11 Asbestos Exposure and Severity of COVID-19 Granados, Galo Sáez-López, María Aljama, Cristina Sampol, Júlia Cruz, María-Jesús Ferrer, Jaume Int J Environ Res Public Health Article Background: The aim of this study was to analyse the relationship between occupational exposure to asbestos and the severity of SARS-CoV-2 infection. Methods: We evaluated patients who survived admission in our centre for COVID-19 pneumonia. Demographic, analytical, and clinical variables were collected during admission. After discharge, a previously validated occupational exposure to asbestos questionnaire was administered. Spirometry, CO diffusion test, the 6-min walk test, and high-resolution chest CT were performed. Patients who required respiratory support (oxygen, CPAP, or NIV) were considered severe. Results: In total, 293 patients (mean age 54 + 13 years) were included. Occupational exposure to asbestos was detected in 67 (24%). Patients with occupational exposure to asbestos had a higher frequency of COVID-19 pneumonia requiring respiratory support (n = 52, 77.6%) than their unexposed peers (n = 139, 61.5%) (p = 0.015). Asbestos exposure was associated with COVID-19 severity in the univariate but not in the multivariate analysis. No differences were found regarding follow-up variables including spirometry and the DLCO diffusion, the 6-min walk test, and CT alterations. Conclusions: In hospitalised patients with COVID-19 pneumonia, those with occupational exposure to asbestos more frequently needed respiratory support. However, an independent association between asbestos exposure and COVID-19 severity could not be confirmed. MDPI 2022-12-06 /pmc/articles/PMC9739528/ /pubmed/36498378 http://dx.doi.org/10.3390/ijerph192316305 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Granados, Galo Sáez-López, María Aljama, Cristina Sampol, Júlia Cruz, María-Jesús Ferrer, Jaume Asbestos Exposure and Severity of COVID-19 |
title | Asbestos Exposure and Severity of COVID-19 |
title_full | Asbestos Exposure and Severity of COVID-19 |
title_fullStr | Asbestos Exposure and Severity of COVID-19 |
title_full_unstemmed | Asbestos Exposure and Severity of COVID-19 |
title_short | Asbestos Exposure and Severity of COVID-19 |
title_sort | asbestos exposure and severity of covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739528/ https://www.ncbi.nlm.nih.gov/pubmed/36498378 http://dx.doi.org/10.3390/ijerph192316305 |
work_keys_str_mv | AT granadosgalo asbestosexposureandseverityofcovid19 AT saezlopezmaria asbestosexposureandseverityofcovid19 AT aljamacristina asbestosexposureandseverityofcovid19 AT sampoljulia asbestosexposureandseverityofcovid19 AT cruzmariajesus asbestosexposureandseverityofcovid19 AT ferrerjaume asbestosexposureandseverityofcovid19 AT asbestosexposureandseverityofcovid19 |