Cargando…

Efficacy, Safety, and Challenges of CAR T-Cells in the Treatment of Solid Tumors

SIMPLE SUMMARY: Chimeric antigen receptor T cells (CAR T-cells) are engineered T cells that target tumor-associated antigens. CAR T-cell therapy is a novel developed immunotherapy initially for destroying hematological malignancies. Its great success in clinical practice of hematological malignancie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Qiuqiang, Lu, Lingeng, Ma, Wenxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739567/ https://www.ncbi.nlm.nih.gov/pubmed/36497465 http://dx.doi.org/10.3390/cancers14235983

Ejemplares similares

CAR T cells in solid tumors: challenges and opportunities
por: Marofi, Faroogh, et al.
Publicado: (2021)

Chimeric-antigen receptor T (CAR-T) cell therapy for solid tumors: challenges and opportunities
por: Xia, An-Liang, et al.
Publicado: (2017)

CAR-T cells and BiTEs in solid tumors: challenges and perspectives
por: Edeline, Julien, et al.
Publicado: (2021)

CAR-NK Cells in the Treatment of Solid Tumors
por: Wrona, Ewa, et al.
Publicado: (2021)

CAR-T cells: Early successes in blood cancer and challenges in solid tumors
por: Dana, Hassan, et al.
Publicado: (2021)

Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors
por: Kosti, Paris, et al.
Publicado: (2021)

New Strategies for the Treatment of Solid Tumors with CAR-T Cells
por: Zhang, Hao, et al.
Publicado: (2016)

CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances
por: Maalej, Karama Makni, et al.
Publicado: (2023)

Current advances and challenges in CAR T-Cell therapy for solid tumors: tumor-associated antigens and the tumor microenvironment
por: Yan, Ting, et al.
Publicado: (2023)

Combination of CAR‑T cell therapy and radiotherapy: Opportunities and challenges in solid tumors (Review)
por: Zhong, Liqiang, et al.
Publicado: (2023)

CAR-T Therapies in Solid Tumors: Opportunities and Challenges
por: Guzman, Grace, et al.
Publicado: (2023)

Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments
por: Dagar, Gunjan, et al.
Publicado: (2023)

Current Progress in CAR-T Cell Therapy for Solid Tumors
por: Ma, Shuo, et al.
Publicado: (2019)

CAR T Cell Locomotion in Solid Tumor Microenvironment
por: Nguyen, Duy T., et al.
Publicado: (2022)

CAR T-Cell Therapy in Children with Solid Tumors
por: Kulczycka, Marika, et al.
Publicado: (2023)

Strategies for Improving the Efficacy of CAR T Cells in Solid Cancers
por: Kyte, Jon Amund
Publicado: (2022)

Emerging Approaches for Solid Tumor Treatment Using CAR-T Cell Therapy
por: Chung, Hyunmin, et al.
Publicado: (2021)

Hurdles to breakthrough in CAR T cell therapy of solid tumors
por: Marofi, Faroogh, et al.
Publicado: (2022)

Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy
por: Li, Hongjun, et al.
Publicado: (2021)

Innovative CAR-T Cell Therapy for Solid Tumor; Current Duel between CAR-T Spear and Tumor Shield
por: Jo, Yuna, et al.
Publicado: (2020)

Engineering CAR T cells for enhanced efficacy and safety
por: Wu, Yiqian, et al.
Publicado: (2022)

Combination therapy: A feasibility strategy for CAR-T cell therapy in the treatment of solid tumors
por: Xu, Jinjing, et al.
Publicado: (2018)

Immunopathological changes, complications, sequelae and immunological memory in COVID-19 patients
por: Yao, Liqin, et al.
Publicado: (2022)

CAR-T cells: the long and winding road to solid tumors
por: D’Aloia, Maria Michela, et al.
Publicado: (2018)

Harnessing the chemokine system to home CAR-T cells into solid tumors
por: Foeng, Jade, et al.
Publicado: (2022)

Advances and Hurdles in CAR T Cell Immune Therapy for Solid Tumors
por: Boccalatte, Francesco, et al.
Publicado: (2022)

CAR T cell therapy in solid tumors: a short review
por: Umut, Öykü, et al.
Publicado: (2021)

Clinical Investigations of CAR-T Cell Therapy for Solid Tumors
por: Chen, Kun, et al.
Publicado: (2022)

CAR-T Cells and Oncolytic Viruses: Joining Forces to Overcome the Solid Tumor Challenge
por: Guedan, Sonia, et al.
Publicado: (2018)

Advancing CAR T-Cell Therapy for Solid Tumors: Lessons Learned from Lymphoma Treatment
por: Titov, Aleksei, et al.
Publicado: (2020)

Breast Cancer Patients: Who Would Benefit from Neoadjuvant Chemotherapies?
por: Yao, Liqin, et al.
Publicado: (2022)

Overhauling CAR T Cells to Improve Efficacy, Safety and Cost
por: Chicaybam, Leonardo, et al.
Publicado: (2020)

Tumor Microenvironment Immunosuppression: A Roadblock to CAR T-Cell Advancement in Solid Tumors
por: Johnson, Abigail, et al.
Publicado: (2022)

Recent Advances in CAR-Based Solid Tumor Immunotherapy
por: Shin, Min Hwa, et al.
Publicado: (2023)

Binding and Efficacy of Anti-Robo4 CAR-T Cells against Solid Tumors
por: Hirobe, Sachiko, et al.
Publicado: (2022)

Improving the anti-solid tumor efficacy of CAR-T cells by inhibiting adenosine signaling pathway
por: Li, Na, et al.
Publicado: (2020)

Making CAR T Cells a Solid Option for Solid Tumors
por: Schmidts, Andrea, et al.
Publicado: (2018)

Challenges of evaluating immunotherapy efficacy in solid tumors
por: Bai, Rilan, et al.
Publicado: (2019)

Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment
por: Scarfò, Irene, et al.
Publicado: (2017)

Chimeric Antigen Receptor T-cell (CAR T) Therapy for Hematologic and Solid Malignancies: Efficacy and Safety—A Systematic Review with Meta-Analysis
por: Yu, Wen-Liang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_pkiam7lm53pihqjohkq3hcrrm3