Cargando…

ERK MAP Kinase Signaling Regulates RAR Signaling to Confer Retinoid Resistance on Breast Cancer Cells

SIMPLE SUMMARY: Breast cancer is among the most common cancers and the leading cause of cancer-related death in women worldwide. Among potential anticancer drugs considered promising in breast cancer treatment are retinoids that act mainly through nuclear retinoic acid receptors (RARs). Clinical tri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hirota, Akira, Clément, Jean-Emmanuel, Tanikawa, Satoshi, Nonoyama, Takayuki, Komatsuzaki, Tamiki, Gong, Jian Ping, Tanaka, Shinya, Imajo, Masamichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739577/ https://www.ncbi.nlm.nih.gov/pubmed/36497371 http://dx.doi.org/10.3390/cancers14235890

Ejemplares similares

Dynamic ERK signaling regulation in intestinal tumorigenesis
por: Muta, Yu, et al.
Publicado: (2018)

Regulation of Retinoid-Mediated Signaling Involved in Skin Homeostasis by RAR and RXR Agonists/Antagonists in Mouse Skin
por: Gericke, Janine, et al.
Publicado: (2013)

Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction
por: Tanikawa, Satoshi, et al.
Publicado: (2023)

Divergent Dynamics and Functions of ERK MAP Kinase Signaling in Development, Homeostasis and Cancer: Lessons from Fluorescent Bioimaging
por: Muta, Yu, et al.
Publicado: (2019)

RAR-Dependent and RAR-Independent RXR Signaling in Stem-like Glioma Cells
por: Dabrock, Amanda, et al.
Publicado: (2023)

Enhancement of Efficacy of Retinoids through Enhancing Retinoid-Induced RAR Activity and Inhibiting Hydroxylation of Retinoic Acid, and Its Clinical Efficacy on Photo-Aging
por: Kang, Seongsu, et al.
Publicado: (2022)

Clinical Pharmacology and Safety of Trifarotene, a First‐in‐Class RARγ‐Selective Topical Retinoid
por: Wagner, Nathalie, et al.
Publicado: (2020)

Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-γ and altered expression of Bcl-2/Bax
por: Pettersson, F, et al.
Publicado: (2002)

RAR/RXR and PPAR/RXR Signaling in Spinal Cord Injury
por: van Neerven, Sabien, et al.
Publicado: (2007)

Signalling with retinoids in the human lung: validation of new tools for the expression study of retinoid receptors
por: Poulain, Stéphane, et al.
Publicado: (2009)

Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)
por: SHILKAITIS, ANNE, et al.
Publicado: (2015)

ATPR triggers acute myeloid leukaemia cells differentiation and cycle arrest via the RARα/LDHB/ERK‐glycolysis signalling axis
por: Du, Yan, et al.
Publicado: (2020)

Editorial
por: Arai, Munehito, et al.
Publicado: (2020)

The Expanding Role for Retinoid Signaling in Heart Development
por: Hoover, Loretta L., et al.
Publicado: (2008)

Retinoid Signaling in Pancreatic Cancer, Injury and Regeneration
por: Colvin, Emily K., et al.
Publicado: (2011)

Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity
por: Nomoto, Masanori, et al.
Publicado: (2012)

Positive feedback loop of IL-1β/Akt/RARα/Akt signaling mediates oncogenic property of RARα in gastric carcinoma
por: Ren, Hong-Yue, et al.
Publicado: (2016)

The retinoid anticancer signal: mechanisms of target gene regulation
por: Liu, T, et al.
Publicado: (2005)

BMP action in skeletogenesis involves attenuation of retinoid signaling
por: Hoffman, Lisa M., et al.
Publicado: (2006)

Long-Distance Retinoid Signaling in the Zebra Finch Brain
por: Roeske, Tina C., et al.
Publicado: (2014)

Vitamin A-retinoid signaling in pulmonary development and disease
por: Marquez, Hector A., et al.
Publicado: (2016)

Anti-inflammatory effects of minocycline are mediated by retinoid signaling
por: Clemens, Vera, et al.
Publicado: (2018)

A Phase 1 Study of IRX195183, a RARα-Selective CYP26 Resistant Retinoid, in Patients With Relapsed or Refractory AML
por: Ambinder, Alexander J., et al.
Publicado: (2020)

Synthetic Retinoid Kills Drug‐Resistant Cancer Stem Cells via Inducing RARγ‐Translocation‐Mediated Tension Reduction and Chromatin Decondensation
por: Zhang, Yao, et al.
Publicado: (2022)

The miR-96 and RARγ signaling axis governs androgen signaling and prostate cancer progression
por: Long, Mark D., et al.
Publicado: (2018)

Expression and Role of IL-1β Signaling in Chondrocytes Associated with Retinoid Signaling during Fracture Healing
por: Shimo, Tsuyoshi, et al.
Publicado: (2020)

Is RARS-T a new disease entity or a subtype of RARS or ET?
por: Bang, Soo-Mee
Publicado: (2010)

Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations
por: le Maire, Albane, et al.
Publicado: (2019)

Regulation of Skeletal Progenitor Differentiation by the Bmp and Retinoid Signaling Pathways
por: Weston, Andrea D., et al.
Publicado: (2000)

FMRP Interacts with RARα in Synaptic Retinoic Acid Signaling and Homeostatic Synaptic Plasticity
por: Park, Esther, et al.
Publicado: (2021)

Transfer entropy dependent on distance among agents in quantifying leader-follower relationships
por: Basak, Udoy S., et al.
Publicado: (2021)

Evolution of Retinoid and Steroid Signaling: Vertebrate Diversification from an Amphioxus Perspective
por: Albalat, Ricard, et al.
Publicado: (2011)

Contribution of Retinoid X Receptor Signaling to the Specification of Skeletal Muscle Lineage
por: Le May, Melanie, et al.
Publicado: (2011)

Dissecting myogenin-mediated retinoid X receptor signaling in myogenic differentiation
por: Khilji, Saadia, et al.
Publicado: (2020)

The quaternary architecture of RARβ–RXRα heterodimer facilitates domain–domain signal transmission
por: Chandra, Vikas, et al.
Publicado: (2017)

Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis
por: Bosch, Almudena, et al.
Publicado: (2012)

Effects of long-term repeated topical fluoride applications and adhesion promoter on shear bond strengths of orthodontic brackets
por: Endo, Toshiya, et al.
Publicado: (2014)

ATP hydrolysis assists phosphate release and promotes reaction ordering in F(1)-ATPase
por: Li, Chun-Biu, et al.
Publicado: (2015)

Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs
por: Koshy, Aysis, et al.
Publicado: (2022)

Symposium on “Retinoid Research and Clinical Application” Supported by the Japanese Cancer Association
por: Shudo, Koichi, et al.
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_n6p5i89rv8neufdtnti9icqu2o