Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent

A convenient protocol was developed for the transformation of N-aryl-substituted benzamides to N-aryl-substituted benzothioamides using N-isopropyldithiocarbamate isopropyl ammonium salt as a novel thiating reagent. The major advantages of this protocol are its one-pot procedure, short reaction time...

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Autores principales: Gomaa, Mohamed S., El Enany, Gaber, Fathalla, Walid, Ali, Ibrahim A. I., El Rayes, Samir. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739585/
https://www.ncbi.nlm.nih.gov/pubmed/36500368
http://dx.doi.org/10.3390/molecules27238275
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author Gomaa, Mohamed S.
El Enany, Gaber
Fathalla, Walid
Ali, Ibrahim A. I.
El Rayes, Samir. M.
author_facet Gomaa, Mohamed S.
El Enany, Gaber
Fathalla, Walid
Ali, Ibrahim A. I.
El Rayes, Samir. M.
author_sort Gomaa, Mohamed S.
collection PubMed
description A convenient protocol was developed for the transformation of N-aryl-substituted benzamides to N-aryl-substituted benzothioamides using N-isopropyldithiocarbamate isopropyl ammonium salt as a novel thiating reagent. The major advantages of this protocol are its one-pot procedure, short reaction times, mild conditions, simple work-up, high yields and pure products.
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spelling pubmed-97395852022-12-11 Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent Gomaa, Mohamed S. El Enany, Gaber Fathalla, Walid Ali, Ibrahim A. I. El Rayes, Samir. M. Molecules Article A convenient protocol was developed for the transformation of N-aryl-substituted benzamides to N-aryl-substituted benzothioamides using N-isopropyldithiocarbamate isopropyl ammonium salt as a novel thiating reagent. The major advantages of this protocol are its one-pot procedure, short reaction times, mild conditions, simple work-up, high yields and pure products. MDPI 2022-11-27 /pmc/articles/PMC9739585/ /pubmed/36500368 http://dx.doi.org/10.3390/molecules27238275 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gomaa, Mohamed S.
El Enany, Gaber
Fathalla, Walid
Ali, Ibrahim A. I.
El Rayes, Samir. M.
Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent
title Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent
title_full Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent
title_fullStr Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent
title_full_unstemmed Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent
title_short Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent
title_sort transformation of amides to thioamides using an efficient and novel thiating reagent
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739585/
https://www.ncbi.nlm.nih.gov/pubmed/36500368
http://dx.doi.org/10.3390/molecules27238275
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