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Unbalanced Glutamine Partitioning between CD8T Cells and Cancer Cells Accompanied by Immune Cell Dysfunction in Hepatocellular Carcinoma

Glutamine metabolism is critical both for the proliferation of cancer cells and the activation of CD8T cells to kill cancer cells. We aim to explore the relationship between the glutamine metabolism of CD8T cells and cancer cells and tumor immunity in the tumor microenvironment. In a TCGA cohort, we...

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Detalles Bibliográficos
Autores principales: Chen, Jianfei, Wang, Rui, Liu, Zhongliang, Fan, Jun, Liu, Shenglu, Tan, Shunde, Li, Xinkai, Li, Bo, Yang, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739589/
https://www.ncbi.nlm.nih.gov/pubmed/36497182
http://dx.doi.org/10.3390/cells11233924

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