GC-MS Analysis of Methadone and EDDP in Addicted Patients under Methadone Substitution Treatment: Comparison of Urine and Plasma as Biological Samples

(1) Background: Methadone, along with buprenorphine, is the most commonly used drug for the treatment of opioid dependence. This study aimed to analyze methadone and its major metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenyl pyrrolidine (EDDP), in the urine and plasma of opiate addicts. The study...

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Detalles Bibliográficos
Autores principales: Ciucă Anghel, Daniela-Mădălina, Ciobanu, Anne-Marie, Guțu, Claudia Maria, Stan, Miriana, Tudor, Gheorghe, Baconi, Daniela Luiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739625/
https://www.ncbi.nlm.nih.gov/pubmed/36500452
http://dx.doi.org/10.3390/molecules27238360

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