Hepatic ROS Mediated Macrophage Activation Is Responsible for Irinotecan Induced Liver Injury

Irinotecan is the first line chemotherapy drug used for treatment of metastatic colorectal cancer worldwide. There is increasing evidence suggesting that liver damage, including steatosis and steatohepatitis, can be caused during the treatment involving irinotecan. However, molecular mechanisms by w...

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Detalles Bibliográficos
Autores principales: Liu, Bohao, Ding, Cong, Tang, Wenbin, Zhang, Chen, Gu, Yiying, Wang, Zhiqiang, Yu, Tingzi, Li, Zhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739808/
https://www.ncbi.nlm.nih.gov/pubmed/36497051
http://dx.doi.org/10.3390/cells11233791

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