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Regular Supplementation with Antioxidants Rescues Doxorubicin-Induced Bone Deformities and Mineralization Delay in Zebrafish

Osteoporosis is characterized by an abnormal bone structure with low bone mass and degradation of microarchitecture. Oxidative stress induces imbalances in osteoblast and osteoclast activity, leading to bone degradation, a primary cause of secondary osteoporosis. Doxorubicin (DOX) is a widely used c...

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Detalles Bibliográficos
Autores principales: Poudel, Sunil, Martins, Gil, Cancela, M. Leonor, Gavaia, Paulo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739841/
https://www.ncbi.nlm.nih.gov/pubmed/36500990
http://dx.doi.org/10.3390/nu14234959