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Main Determinants Affecting the Antiproliferative Activity of Stilbenes and Their Gut Microbiota Metabolites in Colon Cancer Cells: A Structure–Activity Relationship Study
trans-Resveratrol can be catabolized by the gut microbiota to dihydroresveratrol, 3,4′-dihydroxy-trans-stilbene, lunularin, and 4-hydroxydibenzyl. These metabolites can reach relevant concentrations in the colon. However, not all individuals metabolize RSV equally, as it depends on their RSV gut mic...
Autores principales: | González-Sarrías, Antonio, Espín-Aguilar, Juan Carlos, Romero-Reyes, Salvador, Puigcerver, Julio, Alajarín, Mateo, Berná, José, Selma, María Victoria, Espín, Juan Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739882/ https://www.ncbi.nlm.nih.gov/pubmed/36499424 http://dx.doi.org/10.3390/ijms232315102 |
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