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Combined Administration of Pravastatin and Metformin Attenuates Acute Radiation-Induced Intestinal Injury in Mouse and Minipig Models

Radiation-induced gastrointestinal (GI) damage is one of the critical factors that serve as basis for the lethality of nuclear accidents or terrorism. Further, there are no Food and Drug Administration-approved agents available to mitigate radiation-induced intestinal injury. Although pravastatin (P...

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Detalles Bibliográficos
Autores principales: Kim, Jung Moon, Kim, Hyewon, Oh, Su Hyun, Jang, Won Il, Lee, Seung Bum, Park, Mineon, Kim, Soyeon, Park, Sunhoo, Shim, Sehwan, Jang, Hyosun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739896/
https://www.ncbi.nlm.nih.gov/pubmed/36499155
http://dx.doi.org/10.3390/ijms232314827