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TGF-β2 Regulates Transcription of the K(+)/Cl(−) Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons

KCC2 mediates extrusion of K(+) and Cl(−) and assuresthe developmental “switch” in GABA function during neuronal maturation. However, the molecular mechanisms underlying KCC2 regulation are not fully elucidated. We investigated the impact of transforming growth factor beta 2 (TGF-β2) on KCC2 during...

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Detalles Bibliográficos
Autores principales:	Rigkou, Anastasia, Magyar, Attila, Speer, Jan Manuel, Roussa, Eleni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739967/ https://www.ncbi.nlm.nih.gov/pubmed/36497119 http://dx.doi.org/10.3390/cells11233861

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