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A Retrospective Study on Patient-Specific Predictors for Non-Response to Sacroiliac Joint Injections

Intra-articular or peri-articular corticosteroid injections are often used for treatment of sacroiliac joint (SIJ) pain. However, response to these injections is variable and many patients require multiple injections for sustained benefit. In this study, we aim to identify patient-specific predictor...

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Autores principales: Chandrupatla, Rahul S., Shahidi, Bahar, Bruno, Kelly, Chen, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739978/
https://www.ncbi.nlm.nih.gov/pubmed/36497595
http://dx.doi.org/10.3390/ijerph192315519
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author Chandrupatla, Rahul S.
Shahidi, Bahar
Bruno, Kelly
Chen, Jeffrey L.
author_facet Chandrupatla, Rahul S.
Shahidi, Bahar
Bruno, Kelly
Chen, Jeffrey L.
author_sort Chandrupatla, Rahul S.
collection PubMed
description Intra-articular or peri-articular corticosteroid injections are often used for treatment of sacroiliac joint (SIJ) pain. However, response to these injections is variable and many patients require multiple injections for sustained benefit. In this study, we aim to identify patient-specific predictors of response or non-response to SIJ injections. Identification of these predictors would allow providers to better determine what treatment would be appropriate for a patient with SIJ pain. A retrospective review of 100 consecutive patient charts spanning a 2-year period at an academic multi-specialty pain center was conducted and a multivariate regression analysis was used to identify patient-specific predictors of response to SIJ injections. Our analysis identified that a history of depression and anxiety (OR: 0.233, 95%CI: 0.057–0.954) and increased age (OR: 0.946, 95%CI: 0.910–0.984) significantly reduced the odds of responding to injections. We also found that the associated NPRS score change for SIJ injection responders was less than the minimally clinically significant value of a 2-point differential, suggesting that reported changes in pain scores may not accurately represent a patient’s perception of success after SIJ injection. These findings warrant further investigation through a prospective study and can potentially influence clinical decision making and prognosis for patients receiving SIJ injections.
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spelling pubmed-97399782022-12-11 A Retrospective Study on Patient-Specific Predictors for Non-Response to Sacroiliac Joint Injections Chandrupatla, Rahul S. Shahidi, Bahar Bruno, Kelly Chen, Jeffrey L. Int J Environ Res Public Health Article Intra-articular or peri-articular corticosteroid injections are often used for treatment of sacroiliac joint (SIJ) pain. However, response to these injections is variable and many patients require multiple injections for sustained benefit. In this study, we aim to identify patient-specific predictors of response or non-response to SIJ injections. Identification of these predictors would allow providers to better determine what treatment would be appropriate for a patient with SIJ pain. A retrospective review of 100 consecutive patient charts spanning a 2-year period at an academic multi-specialty pain center was conducted and a multivariate regression analysis was used to identify patient-specific predictors of response to SIJ injections. Our analysis identified that a history of depression and anxiety (OR: 0.233, 95%CI: 0.057–0.954) and increased age (OR: 0.946, 95%CI: 0.910–0.984) significantly reduced the odds of responding to injections. We also found that the associated NPRS score change for SIJ injection responders was less than the minimally clinically significant value of a 2-point differential, suggesting that reported changes in pain scores may not accurately represent a patient’s perception of success after SIJ injection. These findings warrant further investigation through a prospective study and can potentially influence clinical decision making and prognosis for patients receiving SIJ injections. MDPI 2022-11-23 /pmc/articles/PMC9739978/ /pubmed/36497595 http://dx.doi.org/10.3390/ijerph192315519 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chandrupatla, Rahul S.
Shahidi, Bahar
Bruno, Kelly
Chen, Jeffrey L.
A Retrospective Study on Patient-Specific Predictors for Non-Response to Sacroiliac Joint Injections
title A Retrospective Study on Patient-Specific Predictors for Non-Response to Sacroiliac Joint Injections
title_full A Retrospective Study on Patient-Specific Predictors for Non-Response to Sacroiliac Joint Injections
title_fullStr A Retrospective Study on Patient-Specific Predictors for Non-Response to Sacroiliac Joint Injections
title_full_unstemmed A Retrospective Study on Patient-Specific Predictors for Non-Response to Sacroiliac Joint Injections
title_short A Retrospective Study on Patient-Specific Predictors for Non-Response to Sacroiliac Joint Injections
title_sort retrospective study on patient-specific predictors for non-response to sacroiliac joint injections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9739978/
https://www.ncbi.nlm.nih.gov/pubmed/36497595
http://dx.doi.org/10.3390/ijerph192315519
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