Cargando…

Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)

Circadian rhythm disruption due to night shift work and/or sleep disorders is associated with negative health outcomes including cancer. There is only scant evidence of an association with lung cancer, unlike breast and prostate cancer. We explore the role of sleep disorders and night shift work in...

Descripción completa

Detalles Bibliográficos
Autores principales: Cordina-Duverger, Emilie, Uchai, Shreeshti, Tvardik, Nastassia, Billmann, Régine, Martin, Diane, Trédaniel, Jean, Wislez, Marie, Blons, Hélène, Laurent-Puig, Pierre, Antoine, Martine, Guénel, Pascal, Radoï, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740028/
https://www.ncbi.nlm.nih.gov/pubmed/36498320
http://dx.doi.org/10.3390/ijerph192316246
_version_ 1784847956622442496
author Cordina-Duverger, Emilie
Uchai, Shreeshti
Tvardik, Nastassia
Billmann, Régine
Martin, Diane
Trédaniel, Jean
Wislez, Marie
Blons, Hélène
Laurent-Puig, Pierre
Antoine, Martine
Guénel, Pascal
Radoï, Loredana
author_facet Cordina-Duverger, Emilie
Uchai, Shreeshti
Tvardik, Nastassia
Billmann, Régine
Martin, Diane
Trédaniel, Jean
Wislez, Marie
Blons, Hélène
Laurent-Puig, Pierre
Antoine, Martine
Guénel, Pascal
Radoï, Loredana
author_sort Cordina-Duverger, Emilie
collection PubMed
description Circadian rhythm disruption due to night shift work and/or sleep disorders is associated with negative health outcomes including cancer. There is only scant evidence of an association with lung cancer, unlike breast and prostate cancer. We explore the role of sleep disorders and night shift work in lung cancer risk among women in a population-based case-control study, including 716 lung cancer cases and 758 controls. Multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) associated with sleep duration per day (<7 h, 7–7.9 h, ≥8 h), a summary index of sleep disorders, chronotype, and night shift work exposure metrics. When compared to women with an average sleep duration of 7–7.9 h per day, the OR was 1.39 (95% CI 1.04–1.86) in long sleepers (≥8 h) and 1.16 (95% CI 0.86–1.56) in short sleepers (<7 h). Overall, lung cancer was not associated with the sleep disorder index, nor with night shift work, regardless of the duration of night work or the frequency of night shifts. However, elevated OR associated with the sleep disorder index were found in the subgroup of current smokers. The U-shaped association of lung cancer with sleep duration was more particularly pronounced among women who worked at night ≥5 years. Our findings suggested that sleep patterns are associated with lung cancer risk in women with a potential modifying effect by night shift work duration or tobacco smoking.
format Online
Article
Text
id pubmed-9740028
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-97400282022-12-11 Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study) Cordina-Duverger, Emilie Uchai, Shreeshti Tvardik, Nastassia Billmann, Régine Martin, Diane Trédaniel, Jean Wislez, Marie Blons, Hélène Laurent-Puig, Pierre Antoine, Martine Guénel, Pascal Radoï, Loredana Int J Environ Res Public Health Article Circadian rhythm disruption due to night shift work and/or sleep disorders is associated with negative health outcomes including cancer. There is only scant evidence of an association with lung cancer, unlike breast and prostate cancer. We explore the role of sleep disorders and night shift work in lung cancer risk among women in a population-based case-control study, including 716 lung cancer cases and 758 controls. Multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) associated with sleep duration per day (<7 h, 7–7.9 h, ≥8 h), a summary index of sleep disorders, chronotype, and night shift work exposure metrics. When compared to women with an average sleep duration of 7–7.9 h per day, the OR was 1.39 (95% CI 1.04–1.86) in long sleepers (≥8 h) and 1.16 (95% CI 0.86–1.56) in short sleepers (<7 h). Overall, lung cancer was not associated with the sleep disorder index, nor with night shift work, regardless of the duration of night work or the frequency of night shifts. However, elevated OR associated with the sleep disorder index were found in the subgroup of current smokers. The U-shaped association of lung cancer with sleep duration was more particularly pronounced among women who worked at night ≥5 years. Our findings suggested that sleep patterns are associated with lung cancer risk in women with a potential modifying effect by night shift work duration or tobacco smoking. MDPI 2022-12-04 /pmc/articles/PMC9740028/ /pubmed/36498320 http://dx.doi.org/10.3390/ijerph192316246 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cordina-Duverger, Emilie
Uchai, Shreeshti
Tvardik, Nastassia
Billmann, Régine
Martin, Diane
Trédaniel, Jean
Wislez, Marie
Blons, Hélène
Laurent-Puig, Pierre
Antoine, Martine
Guénel, Pascal
Radoï, Loredana
Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)
title Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)
title_full Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)
title_fullStr Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)
title_full_unstemmed Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)
title_short Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)
title_sort sleep traits, night shift work and lung cancer risk among women: results from a population-based case-control study in france (the welca study)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740028/
https://www.ncbi.nlm.nih.gov/pubmed/36498320
http://dx.doi.org/10.3390/ijerph192316246
work_keys_str_mv AT cordinaduvergeremilie sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT uchaishreeshti sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT tvardiknastassia sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT billmannregine sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT martindiane sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT tredanieljean sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT wislezmarie sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT blonshelene sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT laurentpuigpierre sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT antoinemartine sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT guenelpascal sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT radoiloredana sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy
AT sleeptraitsnightshiftworkandlungcancerriskamongwomenresultsfromapopulationbasedcasecontrolstudyinfrancethewelcastudy