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Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study)
Circadian rhythm disruption due to night shift work and/or sleep disorders is associated with negative health outcomes including cancer. There is only scant evidence of an association with lung cancer, unlike breast and prostate cancer. We explore the role of sleep disorders and night shift work in...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740028/ https://www.ncbi.nlm.nih.gov/pubmed/36498320 http://dx.doi.org/10.3390/ijerph192316246 |
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author | Cordina-Duverger, Emilie Uchai, Shreeshti Tvardik, Nastassia Billmann, Régine Martin, Diane Trédaniel, Jean Wislez, Marie Blons, Hélène Laurent-Puig, Pierre Antoine, Martine Guénel, Pascal Radoï, Loredana |
author_facet | Cordina-Duverger, Emilie Uchai, Shreeshti Tvardik, Nastassia Billmann, Régine Martin, Diane Trédaniel, Jean Wislez, Marie Blons, Hélène Laurent-Puig, Pierre Antoine, Martine Guénel, Pascal Radoï, Loredana |
author_sort | Cordina-Duverger, Emilie |
collection | PubMed |
description | Circadian rhythm disruption due to night shift work and/or sleep disorders is associated with negative health outcomes including cancer. There is only scant evidence of an association with lung cancer, unlike breast and prostate cancer. We explore the role of sleep disorders and night shift work in lung cancer risk among women in a population-based case-control study, including 716 lung cancer cases and 758 controls. Multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) associated with sleep duration per day (<7 h, 7–7.9 h, ≥8 h), a summary index of sleep disorders, chronotype, and night shift work exposure metrics. When compared to women with an average sleep duration of 7–7.9 h per day, the OR was 1.39 (95% CI 1.04–1.86) in long sleepers (≥8 h) and 1.16 (95% CI 0.86–1.56) in short sleepers (<7 h). Overall, lung cancer was not associated with the sleep disorder index, nor with night shift work, regardless of the duration of night work or the frequency of night shifts. However, elevated OR associated with the sleep disorder index were found in the subgroup of current smokers. The U-shaped association of lung cancer with sleep duration was more particularly pronounced among women who worked at night ≥5 years. Our findings suggested that sleep patterns are associated with lung cancer risk in women with a potential modifying effect by night shift work duration or tobacco smoking. |
format | Online Article Text |
id | pubmed-9740028 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97400282022-12-11 Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study) Cordina-Duverger, Emilie Uchai, Shreeshti Tvardik, Nastassia Billmann, Régine Martin, Diane Trédaniel, Jean Wislez, Marie Blons, Hélène Laurent-Puig, Pierre Antoine, Martine Guénel, Pascal Radoï, Loredana Int J Environ Res Public Health Article Circadian rhythm disruption due to night shift work and/or sleep disorders is associated with negative health outcomes including cancer. There is only scant evidence of an association with lung cancer, unlike breast and prostate cancer. We explore the role of sleep disorders and night shift work in lung cancer risk among women in a population-based case-control study, including 716 lung cancer cases and 758 controls. Multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) associated with sleep duration per day (<7 h, 7–7.9 h, ≥8 h), a summary index of sleep disorders, chronotype, and night shift work exposure metrics. When compared to women with an average sleep duration of 7–7.9 h per day, the OR was 1.39 (95% CI 1.04–1.86) in long sleepers (≥8 h) and 1.16 (95% CI 0.86–1.56) in short sleepers (<7 h). Overall, lung cancer was not associated with the sleep disorder index, nor with night shift work, regardless of the duration of night work or the frequency of night shifts. However, elevated OR associated with the sleep disorder index were found in the subgroup of current smokers. The U-shaped association of lung cancer with sleep duration was more particularly pronounced among women who worked at night ≥5 years. Our findings suggested that sleep patterns are associated with lung cancer risk in women with a potential modifying effect by night shift work duration or tobacco smoking. MDPI 2022-12-04 /pmc/articles/PMC9740028/ /pubmed/36498320 http://dx.doi.org/10.3390/ijerph192316246 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cordina-Duverger, Emilie Uchai, Shreeshti Tvardik, Nastassia Billmann, Régine Martin, Diane Trédaniel, Jean Wislez, Marie Blons, Hélène Laurent-Puig, Pierre Antoine, Martine Guénel, Pascal Radoï, Loredana Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study) |
title | Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study) |
title_full | Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study) |
title_fullStr | Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study) |
title_full_unstemmed | Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study) |
title_short | Sleep Traits, Night Shift Work and Lung Cancer Risk among Women: Results from a Population-Based Case-Control Study in France (The WELCA Study) |
title_sort | sleep traits, night shift work and lung cancer risk among women: results from a population-based case-control study in france (the welca study) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740028/ https://www.ncbi.nlm.nih.gov/pubmed/36498320 http://dx.doi.org/10.3390/ijerph192316246 |
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