Amorphous Solid Dispersion of Hesperidin with Polymer Excipients for Enhanced Apparent Solubility as a More Effective Approach to the Treatment of Civilization Diseases

The present study reports amorphous solid dispersions (ASDs) of hesperidin (Hes) prepared by ball milling to improve its solubility and apparent solubility over the unmodified compound. The carriers were Soluplus(®) (Sol), alginate sodium (SA), and hydroxypropylmethylcellulose (HPMC). XRPD analysis...

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Detalles Bibliográficos
Autores principales: Rosiak, Natalia, Wdowiak, Kamil, Tykarska, Ewa, Cielecka-Piontek, Judyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740072/
https://www.ncbi.nlm.nih.gov/pubmed/36499518
http://dx.doi.org/10.3390/ijms232315198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740072/
https://www.ncbi.nlm.nih.gov/pubmed/36499518
http://dx.doi.org/10.3390/ijms232315198

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