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Amorphous Solid Dispersion of Hesperidin with Polymer Excipients for Enhanced Apparent Solubility as a More Effective Approach to the Treatment of Civilization Diseases
The present study reports amorphous solid dispersions (ASDs) of hesperidin (Hes) prepared by ball milling to improve its solubility and apparent solubility over the unmodified compound. The carriers were Soluplus(®) (Sol), alginate sodium (SA), and hydroxypropylmethylcellulose (HPMC). XRPD analysis...
Autores principales: | Rosiak, Natalia, Wdowiak, Kamil, Tykarska, Ewa, Cielecka-Piontek, Judyta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740072/ https://www.ncbi.nlm.nih.gov/pubmed/36499518 http://dx.doi.org/10.3390/ijms232315198 |
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