Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers

The aggregation of α-synuclein (α-syn) into neurotoxic oligomers and fibrils is an important pathogenic feature of synucleinopatheis, including Parkinson’s disease (PD). A further characteristic of PD is the oxidative stress that results in the formation of aldehydes by lipid peroxidation. It has be...

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Detalles Bibliográficos
Autores principales: Vaikath, Nishant, Sudhakaran, Indulekha, Abdi, Ilham, Gupta, Vijay, Majbour, Nour, Ghanem, Simona, Abdesselem, Houari, Vekrellis, Kostas, El-Agnaf, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740078/
https://www.ncbi.nlm.nih.gov/pubmed/36498957
http://dx.doi.org/10.3390/ijms232314630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740078/
https://www.ncbi.nlm.nih.gov/pubmed/36498957
http://dx.doi.org/10.3390/ijms232314630

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