Cargando…
DGCR8 Microprocessor Subunit Mutation and Expression Deregulation in Thyroid Lesions
DGCR8 emerged recently as miRNAs biogenesis pathway protein with a highlighted role in thyroid disease. This study aimed to characterize this miRNA biogenesis component, in particular the p.(E518K) mutation and DGCR8 expression in a series of thyroid lesions. The series of thyroid lesions was genoty...
Autores principales: | Rodrigues, Lia, Canberk, Sule, Macedo, Sofia, Soares, Paula, Vinagre, João |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740158/ https://www.ncbi.nlm.nih.gov/pubmed/36499151 http://dx.doi.org/10.3390/ijms232314812 |
Ejemplares similares
-
DGCR8 HITS-CLIP reveals novel functions for the Microprocessor
por: Macias, Sara, et al.
Publicado: (2012) -
Genomic Analysis Suggests that mRNA Destabilization by the Microprocessor Is Specialized for the Auto-Regulation of Dgcr8
por: Shenoy, Archana, et al.
Publicado: (2009) -
Partial Disturbance of Microprocessor Function in Human Stem Cells Carrying a Heterozygous Mutation in the DGCR8 Gene
por: Reé, Dóra, et al.
Publicado: (2022) -
An essential microRNA maturing microprocessor complex component DGCR8 is up-regulated in colorectal carcinomas
por: Kim, Bora, et al.
Publicado: (2013) -
Whole-genome Sequencing of Follicular Thyroid Carcinomas Reveal Recurrent Mutations in MicroRNA Processing Subunit DGCR8
por: Paulsson, Johan O, et al.
Publicado: (2021)