Comparative Pharmacokinetics and Tissue Distribution of M10 and Its Metabolite Myricetin in Normal and Dextran-Sodium-Sulfate-Induced Colitis Mice

M10, a novel myricetin derivative, is an anti-inflammatory agent designed for treatment of colitis. Here, we aim to investigate its pharmacokinetic behavior and tissue distribution in a mouse model with colitis. Pharmacokinetics and tissue distribution of M10 and its metabolite myricetin were compar...

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Detalles Bibliográficos
Autores principales: Zhao, Jianchun, Yuan, Wenmin, Wang, Shixiao, Zhang, Hongwei, Chen, Dan, Niu, Xiaochen, Liu, Xiaochun, Liu, Li, Gao, Jiangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740244/
https://www.ncbi.nlm.nih.gov/pubmed/36500233
http://dx.doi.org/10.3390/molecules27238140

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