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Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings
The COVID-19 pandemic has increased the need for developing disinfectant surfaces as well as reducing the spread of infections on contaminated surfaces and the contamination risk from the fomite route. The present work reports on the antiviral activity of coatings containing ZnO particles obtained b...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740257/ https://www.ncbi.nlm.nih.gov/pubmed/36500967 http://dx.doi.org/10.3390/nano12234345 |
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author | Primo, Julia de O. Correa, Jamille de S. Horsth, Dienifer F. L. Das, Arkaprava Zając, Marcin Umek, Polona Wattiez, Ruddy Anaissi, Fauze J. Onderwater, Rob C. A. Bittencourt, Carla |
author_facet | Primo, Julia de O. Correa, Jamille de S. Horsth, Dienifer F. L. Das, Arkaprava Zając, Marcin Umek, Polona Wattiez, Ruddy Anaissi, Fauze J. Onderwater, Rob C. A. Bittencourt, Carla |
author_sort | Primo, Julia de O. |
collection | PubMed |
description | The COVID-19 pandemic has increased the need for developing disinfectant surfaces as well as reducing the spread of infections on contaminated surfaces and the contamination risk from the fomite route. The present work reports on the antiviral activity of coatings containing ZnO particles obtained by two simple synthesis routes using Aloe vera (ZnO-aloe) or cassava starch (ZnO-starch) as reaction fuel. After detailed characterization using XRD and NEXAFS, the obtained ZnO particles were dispersed in a proportion of 10% with two different waterborne acrylic coatings (binder and commercial white paint) and brushed on the surface of polycarbonates (PC). The cured ZnO/coatings were characterized by scanning electron microscopes (SEM) and energy-dispersive X-ray spectroscopy (EDS). Wettability tests were performed. The virucidal activity of the ZnO particles dispersed in the waterborne acrylic coating was compared to a reference control sample (PC plates). According to RT-PCR results, the ZnO-aloe/coating displays the highest outcome for antiviral activity against SARS-CoV-2 using the acrylic binder, inactivating >99% of the virus after 24 h of contact relative to reference control. |
format | Online Article Text |
id | pubmed-9740257 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97402572022-12-11 Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings Primo, Julia de O. Correa, Jamille de S. Horsth, Dienifer F. L. Das, Arkaprava Zając, Marcin Umek, Polona Wattiez, Ruddy Anaissi, Fauze J. Onderwater, Rob C. A. Bittencourt, Carla Nanomaterials (Basel) Article The COVID-19 pandemic has increased the need for developing disinfectant surfaces as well as reducing the spread of infections on contaminated surfaces and the contamination risk from the fomite route. The present work reports on the antiviral activity of coatings containing ZnO particles obtained by two simple synthesis routes using Aloe vera (ZnO-aloe) or cassava starch (ZnO-starch) as reaction fuel. After detailed characterization using XRD and NEXAFS, the obtained ZnO particles were dispersed in a proportion of 10% with two different waterborne acrylic coatings (binder and commercial white paint) and brushed on the surface of polycarbonates (PC). The cured ZnO/coatings were characterized by scanning electron microscopes (SEM) and energy-dispersive X-ray spectroscopy (EDS). Wettability tests were performed. The virucidal activity of the ZnO particles dispersed in the waterborne acrylic coating was compared to a reference control sample (PC plates). According to RT-PCR results, the ZnO-aloe/coating displays the highest outcome for antiviral activity against SARS-CoV-2 using the acrylic binder, inactivating >99% of the virus after 24 h of contact relative to reference control. MDPI 2022-12-06 /pmc/articles/PMC9740257/ /pubmed/36500967 http://dx.doi.org/10.3390/nano12234345 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Primo, Julia de O. Correa, Jamille de S. Horsth, Dienifer F. L. Das, Arkaprava Zając, Marcin Umek, Polona Wattiez, Ruddy Anaissi, Fauze J. Onderwater, Rob C. A. Bittencourt, Carla Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings |
title | Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings |
title_full | Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings |
title_fullStr | Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings |
title_full_unstemmed | Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings |
title_short | Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings |
title_sort | antiviral properties against sars-cov-2 of nanostructured zno obtained by green combustion synthesis and coated in waterborne acrylic coatings |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740257/ https://www.ncbi.nlm.nih.gov/pubmed/36500967 http://dx.doi.org/10.3390/nano12234345 |
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