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Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings

The COVID-19 pandemic has increased the need for developing disinfectant surfaces as well as reducing the spread of infections on contaminated surfaces and the contamination risk from the fomite route. The present work reports on the antiviral activity of coatings containing ZnO particles obtained b...

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Autores principales: Primo, Julia de O., Correa, Jamille de S., Horsth, Dienifer F. L., Das, Arkaprava, Zając, Marcin, Umek, Polona, Wattiez, Ruddy, Anaissi, Fauze J., Onderwater, Rob C. A., Bittencourt, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740257/
https://www.ncbi.nlm.nih.gov/pubmed/36500967
http://dx.doi.org/10.3390/nano12234345
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author Primo, Julia de O.
Correa, Jamille de S.
Horsth, Dienifer F. L.
Das, Arkaprava
Zając, Marcin
Umek, Polona
Wattiez, Ruddy
Anaissi, Fauze J.
Onderwater, Rob C. A.
Bittencourt, Carla
author_facet Primo, Julia de O.
Correa, Jamille de S.
Horsth, Dienifer F. L.
Das, Arkaprava
Zając, Marcin
Umek, Polona
Wattiez, Ruddy
Anaissi, Fauze J.
Onderwater, Rob C. A.
Bittencourt, Carla
author_sort Primo, Julia de O.
collection PubMed
description The COVID-19 pandemic has increased the need for developing disinfectant surfaces as well as reducing the spread of infections on contaminated surfaces and the contamination risk from the fomite route. The present work reports on the antiviral activity of coatings containing ZnO particles obtained by two simple synthesis routes using Aloe vera (ZnO-aloe) or cassava starch (ZnO-starch) as reaction fuel. After detailed characterization using XRD and NEXAFS, the obtained ZnO particles were dispersed in a proportion of 10% with two different waterborne acrylic coatings (binder and commercial white paint) and brushed on the surface of polycarbonates (PC). The cured ZnO/coatings were characterized by scanning electron microscopes (SEM) and energy-dispersive X-ray spectroscopy (EDS). Wettability tests were performed. The virucidal activity of the ZnO particles dispersed in the waterborne acrylic coating was compared to a reference control sample (PC plates). According to RT-PCR results, the ZnO-aloe/coating displays the highest outcome for antiviral activity against SARS-CoV-2 using the acrylic binder, inactivating >99% of the virus after 24 h of contact relative to reference control.
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spelling pubmed-97402572022-12-11 Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings Primo, Julia de O. Correa, Jamille de S. Horsth, Dienifer F. L. Das, Arkaprava Zając, Marcin Umek, Polona Wattiez, Ruddy Anaissi, Fauze J. Onderwater, Rob C. A. Bittencourt, Carla Nanomaterials (Basel) Article The COVID-19 pandemic has increased the need for developing disinfectant surfaces as well as reducing the spread of infections on contaminated surfaces and the contamination risk from the fomite route. The present work reports on the antiviral activity of coatings containing ZnO particles obtained by two simple synthesis routes using Aloe vera (ZnO-aloe) or cassava starch (ZnO-starch) as reaction fuel. After detailed characterization using XRD and NEXAFS, the obtained ZnO particles were dispersed in a proportion of 10% with two different waterborne acrylic coatings (binder and commercial white paint) and brushed on the surface of polycarbonates (PC). The cured ZnO/coatings were characterized by scanning electron microscopes (SEM) and energy-dispersive X-ray spectroscopy (EDS). Wettability tests were performed. The virucidal activity of the ZnO particles dispersed in the waterborne acrylic coating was compared to a reference control sample (PC plates). According to RT-PCR results, the ZnO-aloe/coating displays the highest outcome for antiviral activity against SARS-CoV-2 using the acrylic binder, inactivating >99% of the virus after 24 h of contact relative to reference control. MDPI 2022-12-06 /pmc/articles/PMC9740257/ /pubmed/36500967 http://dx.doi.org/10.3390/nano12234345 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Primo, Julia de O.
Correa, Jamille de S.
Horsth, Dienifer F. L.
Das, Arkaprava
Zając, Marcin
Umek, Polona
Wattiez, Ruddy
Anaissi, Fauze J.
Onderwater, Rob C. A.
Bittencourt, Carla
Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings
title Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings
title_full Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings
title_fullStr Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings
title_full_unstemmed Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings
title_short Antiviral Properties against SARS-CoV-2 of Nanostructured ZnO Obtained by Green Combustion Synthesis and Coated in Waterborne Acrylic Coatings
title_sort antiviral properties against sars-cov-2 of nanostructured zno obtained by green combustion synthesis and coated in waterborne acrylic coatings
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740257/
https://www.ncbi.nlm.nih.gov/pubmed/36500967
http://dx.doi.org/10.3390/nano12234345
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