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Identification and Comparison of Bioactive Components of Two Dryopteris sp. Extract Using LC-QTOF-MS

Dryopteris sp. is known for its various pharmacological effects and is used as a traditional medicine in Asia. The present study investigated the chemical composition and antimicrobial activity of Dryopteris sp. distributed in Korea. The chemical compounds in the ethanolic extracts of Dryopteris lac...

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Autores principales: Kim, Yangseon, Lim, Da Jung, Song, Jeong-Sup, Kim, Jung-Ae, Lee, Byoung-Hee, Son, Youn Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740439/
https://www.ncbi.nlm.nih.gov/pubmed/36501275
http://dx.doi.org/10.3390/plants11233233
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author Kim, Yangseon
Lim, Da Jung
Song, Jeong-Sup
Kim, Jung-Ae
Lee, Byoung-Hee
Son, Youn Kyoung
author_facet Kim, Yangseon
Lim, Da Jung
Song, Jeong-Sup
Kim, Jung-Ae
Lee, Byoung-Hee
Son, Youn Kyoung
author_sort Kim, Yangseon
collection PubMed
description Dryopteris sp. is known for its various pharmacological effects and is used as a traditional medicine in Asia. The present study investigated the chemical composition and antimicrobial activity of Dryopteris sp. distributed in Korea. The chemical compounds in the ethanolic extracts of Dryopteris lacera and Dryopteris bissetiana were investigated by ultra-high performance liquid chromatography–quadrupole time-of-flight–mass spectrometry analysis and identified by exploring the UNIFI traditional medicine library. Flavonoids such as juglanin, 6-hydroxyluteolin 7-O-laminaribioside, peltatoside, kaempferitrin, hyperoside, and astragalin were identified in both D. lacera and D. bissetiana. Neochlorogenic acid was identified as a caffeoylquinic acid in D. bissetiana. Both extracts of D. lacera and D. bissetiana exhibited antibacterial activity against Gram-positive pathogens, Staphylococcus aureus and Streptococcus mutans. The minimum inhibitory concentration of D. bissetiana against S. aureus was less than 625 ppm. The antibacterial activity was attributed to the identified phenolic compounds, juglanin, 6-hydroxyluteolin 7-O-laminaribioside, kaempferitrin, astragalin, and neochlorogenic acid. Therefore, D. lacera and D. bissetiana can be used as Gram-positive selective antibiotics for further investigation.
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spelling pubmed-97404392022-12-11 Identification and Comparison of Bioactive Components of Two Dryopteris sp. Extract Using LC-QTOF-MS Kim, Yangseon Lim, Da Jung Song, Jeong-Sup Kim, Jung-Ae Lee, Byoung-Hee Son, Youn Kyoung Plants (Basel) Communication Dryopteris sp. is known for its various pharmacological effects and is used as a traditional medicine in Asia. The present study investigated the chemical composition and antimicrobial activity of Dryopteris sp. distributed in Korea. The chemical compounds in the ethanolic extracts of Dryopteris lacera and Dryopteris bissetiana were investigated by ultra-high performance liquid chromatography–quadrupole time-of-flight–mass spectrometry analysis and identified by exploring the UNIFI traditional medicine library. Flavonoids such as juglanin, 6-hydroxyluteolin 7-O-laminaribioside, peltatoside, kaempferitrin, hyperoside, and astragalin were identified in both D. lacera and D. bissetiana. Neochlorogenic acid was identified as a caffeoylquinic acid in D. bissetiana. Both extracts of D. lacera and D. bissetiana exhibited antibacterial activity against Gram-positive pathogens, Staphylococcus aureus and Streptococcus mutans. The minimum inhibitory concentration of D. bissetiana against S. aureus was less than 625 ppm. The antibacterial activity was attributed to the identified phenolic compounds, juglanin, 6-hydroxyluteolin 7-O-laminaribioside, kaempferitrin, astragalin, and neochlorogenic acid. Therefore, D. lacera and D. bissetiana can be used as Gram-positive selective antibiotics for further investigation. MDPI 2022-11-25 /pmc/articles/PMC9740439/ /pubmed/36501275 http://dx.doi.org/10.3390/plants11233233 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Kim, Yangseon
Lim, Da Jung
Song, Jeong-Sup
Kim, Jung-Ae
Lee, Byoung-Hee
Son, Youn Kyoung
Identification and Comparison of Bioactive Components of Two Dryopteris sp. Extract Using LC-QTOF-MS
title Identification and Comparison of Bioactive Components of Two Dryopteris sp. Extract Using LC-QTOF-MS
title_full Identification and Comparison of Bioactive Components of Two Dryopteris sp. Extract Using LC-QTOF-MS
title_fullStr Identification and Comparison of Bioactive Components of Two Dryopteris sp. Extract Using LC-QTOF-MS
title_full_unstemmed Identification and Comparison of Bioactive Components of Two Dryopteris sp. Extract Using LC-QTOF-MS
title_short Identification and Comparison of Bioactive Components of Two Dryopteris sp. Extract Using LC-QTOF-MS
title_sort identification and comparison of bioactive components of two dryopteris sp. extract using lc-qtof-ms
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740439/
https://www.ncbi.nlm.nih.gov/pubmed/36501275
http://dx.doi.org/10.3390/plants11233233
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