Cargando…

Neuroprotective Epigenetic Changes Induced by Maternal Treatment with an Inhibitor of Soluble Epoxide Hydrolase Prevents Early Alzheimer′s Disease Neurodegeneration

Modulation of Alzheimer′s disease (AD) risk begins early in life. During embryo development and postnatal maturation, the brain receives maternal physiological influences and establishes epigenetic patterns that build its level of resilience to late-life diseases. The soluble epoxide hydrolase inhib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bartra, Clara, Irisarri, Alba, Villoslada, Ainhoa, Corpas, Rubén, Aguirre, Samuel, García-Lara, Elisa, Suñol, Cristina, Pallàs, Mercè, Griñán-Ferré, Christian, Sanfeliu, Coral
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740580/ https://www.ncbi.nlm.nih.gov/pubmed/36499477 http://dx.doi.org/10.3390/ijms232315151

Ejemplares similares

Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson’s Disease: A New Therapeutic Strategy
por: Pallàs, Mercè, et al.
Publicado: (2020)

Understanding Epigenetics in the Neurodegeneration of Alzheimer’s Disease: SAMP8 Mouse Model
por: Griñán-Ferré, Christian, et al.
Publicado: (2018)

From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
por: Codony, Sandra, et al.
Publicado: (2021)

Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer’s Disease
por: Codony, Sandra, et al.
Publicado: (2022)

Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
por: Codony, Sandra, et al.
Publicado: (2022)

A Combined Chronic Low-Dose Soluble Epoxide Hydrolase and Acetylcholinesterase Pharmacological Inhibition Promotes Memory Reinstatement in Alzheimer’s Disease Mice Models
por: Jarne-Ferrer, Júlia, et al.
Publicado: (2022)

2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity
por: Martín-López, Juan, et al.
Publicado: (2021)

Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease
por: Griñán-Ferré, Christian, et al.
Publicado: (2021)

Environmental Enrichment Improves Cognitive Deficits, AD Hallmarks and Epigenetic Alterations Presented in 5xFAD Mouse Model
por: Griñán-Ferré, Christian, et al.
Publicado: (2018)

Soluble Epoxide Hydrolase in Atherosclerosis
por: Wang, Yi-Xin Jim, et al.
Publicado: (2010)

Cognitive Decline and BPSD Are Concomitant with Autophagic and Synaptic Deficits Associated with G9a Alterations in Aged SAMP8 Mice
por: Vasilopoulou, Foteini, et al.
Publicado: (2022)

Soluble Epoxide Hydrolase and Diabetes Complications
por: Anita, Natasha Z., et al.
Publicado: (2022)

Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice
por: Griñán-Ferré, Christian, et al.
Publicado: (2016)

Inhibition of Soluble Epoxide Hydrolase for Renal Health
por: Liu, Jun-Yan
Publicado: (2019)

Soluble Epoxide Hydrolase and Brain Cholesterol Metabolism
por: Domingues, Michelle Flores, et al.
Publicado: (2020)

Soluble Epoxide Hydrolase Derived Linoleic Acid Oxylipins, Small Vessel Disease Markers, and Neurodegeneration in Stroke
por: Yu, Di, et al.
Publicado: (2022)

Evaluation of fish models of soluble epoxide hydrolase inhibition.
por: Newman, J W, et al.
Publicado: (2001)

Disrupting Dimerization Translocates Soluble Epoxide Hydrolase to Peroxisomes
por: Nelson, Jonathan W., et al.
Publicado: (2016)

Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors
por: Imig, John D., et al.
Publicado: (2020)

The role of soluble epoxide hydrolase and its inhibitors in depression
por: Borsini, Alessandra
Publicado: (2021)

Peripheral Maintenance of the Axis SIRT1-SIRT3 at Youth Level May Contribute to Brain Resilience in Middle-Aged Amateur Rugby Players
por: Corpas, Rubén, et al.
Publicado: (2019)

Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors
por: Kodani, Sean D., et al.
Publicado: (2018)

Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation
por: Brenneis, Christian, et al.
Publicado: (2011)

Effects of Soluble Epoxide Hydrolase Deficiency on Acute Pancreatitis in Mice
por: Bettaieb, Ahmed, et al.
Publicado: (2014)

Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice
por: Qin, Jun, et al.
Publicado: (2015)

Dysregulation of Soluble Epoxide Hydrolase and Lipidomic Profiles in Anorexia Nervosa
por: Shih, Pei-an Betty, et al.
Publicado: (2015)

Discovery of Novel Soluble Epoxide Hydrolase Inhibitors as Potent Vasodilators
por: Tripathi, Neetika, et al.
Publicado: (2018)

Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future
por: Park, Bomina, et al.
Publicado: (2019)

Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis
por: McReynolds, Cindy B., et al.
Publicado: (2019)

Soluble Epoxide Hydrolase as a Therapeutic Target for Neuropsychiatric Disorders
por: Shan, Jiajing, et al.
Publicado: (2022)

Inhibitory Activity of Quaternary Isoquinoline Alkaloids on Soluble Epoxide Hydrolase
por: Kim, Jang Hoon, et al.
Publicado: (2022)

Inhibition of Soluble Epoxide Hydrolase Activity by Components of Glycyrrhiza uralensis
por: Kim, Jang Hoon, et al.
Publicado: (2023)

Soluble epoxide hydrolase inhibitor promotes the healing of oral ulcers
por: Li, Juanjuan, et al.
Publicado: (2023)

Antibody Protection against Long-Term Memory Loss Induced by Monomeric C-Reactive Protein in a Mouse Model of Dementia
por: García-Lara, Elisa, et al.
Publicado: (2021)

Synergistic Neuroprotective Effects of a Natural Product Mixture against AD Hallmarks and Cognitive Decline in Caenorhabditis elegans and an SAMP8 Mice Model
por: Griñán-Ferré, Christian, et al.
Publicado: (2021)

Role of Endothelial Soluble Epoxide Hydrolase in Cerebrovascular Function and Ischemic Injury
por: Zhang, Wenri, et al.
Publicado: (2013)

Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice
por: Zhu, Ye, et al.
Publicado: (2016)

Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium
por: Serrano-Hervás, Eila, et al.
Publicado: (2017)

Role of Soluble Epoxide Hydrolase in Metabolism of PUFAs in Psychiatric and Neurological Disorders
por: Hashimoto, Kenji
Publicado: (2019)

Vascular repair and anti-inflammatory effects of soluble epoxide hydrolase inhibitor
por: Dai, Na, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ild07ckv1clpa1q9stiumo2pah