Cargando…
Association between PM(1) Exposure and Lung Function in Children and Adolescents: A Systematic Review and Meta-Analysis
The detrimental effects of PM(2.5) and PM(10) (particulate matter less than 2.5 or 10 μm) on human respiratory system, including lung function, have been widely assessed. However, the associations between PM(1) (particulate matter of less than 1 μm) and lung function in children and adolescents are...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740616/ https://www.ncbi.nlm.nih.gov/pubmed/36497960 http://dx.doi.org/10.3390/ijerph192315888 |
_version_ | 1784848108649185280 |
---|---|
author | Zong, Zhiqiang Zhao, Mengjie Zhang, Mengyue Xu, Kexin Zhang, Yunquan Zhang, Xiujun Hu, Chengyang |
author_facet | Zong, Zhiqiang Zhao, Mengjie Zhang, Mengyue Xu, Kexin Zhang, Yunquan Zhang, Xiujun Hu, Chengyang |
author_sort | Zong, Zhiqiang |
collection | PubMed |
description | The detrimental effects of PM(2.5) and PM(10) (particulate matter less than 2.5 or 10 μm) on human respiratory system, including lung function, have been widely assessed. However, the associations between PM(1) (particulate matter of less than 1 μm) and lung function in children and adolescents are less explored, and current evidence is inconsistent. We conducted a meta-analysis of the literature on the association between PM(1) and lung function in children and adolescents to fill this gap. With no date or language constraints, we used a combination of MeSH (Medical Subject Headings) terms and free text to search PubMed, EMBASE and Web of Science databases through, 1 October 2022 for “PM(1) exposure” and “lung function”. A total of 6420 relevant studies were identified through our initial search, and seven studies were included in our study. In this meta-analysis, the fixed effect and random effects statistical models were used to estimate the synthesized effects of the seven included studies. For every 10 μg/m(3) increase in short-term PM(1) exposure, forced vital capacity (FVC), forced expiratory volume in the first second (FEV(1)), peak expiratory flow (PEF) and maximal mid-expiratory flow (MMEF) decreased by 31.82 mL (95% CI: 20.18, 43.45), 32.28 mL (95% CI: 16.73, 48.91), 36.85 mL/s (95% CI: 15.33, 58.38) and 34.51 mL/s (95% CI: 19.61, 49.41), respectively. For each 10 μg/m(3) increase in long-term PM(1) exposure, FVC, FEV(1), PEF and MMEF decreased by 102.34 mL (95% CI: 49.30, 155.38), 75.17 mL (95% CI: 39.61, 110.73), 119.01 mL/s (95% CI: 72.14, 165.88) and 44.94 mL/s (95% CI: 4.70, 85.18), respectively. Our study provides further scientific evidence for the harmful effects of PM(1) exposure on lung function in children and adolescents, indicating that exposure to PM(1) is detrimental to pulmonary health. To reduce the adverse health effects of air pollution on children and adolescents, effective preventive measures should be taken. |
format | Online Article Text |
id | pubmed-9740616 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97406162022-12-11 Association between PM(1) Exposure and Lung Function in Children and Adolescents: A Systematic Review and Meta-Analysis Zong, Zhiqiang Zhao, Mengjie Zhang, Mengyue Xu, Kexin Zhang, Yunquan Zhang, Xiujun Hu, Chengyang Int J Environ Res Public Health Systematic Review The detrimental effects of PM(2.5) and PM(10) (particulate matter less than 2.5 or 10 μm) on human respiratory system, including lung function, have been widely assessed. However, the associations between PM(1) (particulate matter of less than 1 μm) and lung function in children and adolescents are less explored, and current evidence is inconsistent. We conducted a meta-analysis of the literature on the association between PM(1) and lung function in children and adolescents to fill this gap. With no date or language constraints, we used a combination of MeSH (Medical Subject Headings) terms and free text to search PubMed, EMBASE and Web of Science databases through, 1 October 2022 for “PM(1) exposure” and “lung function”. A total of 6420 relevant studies were identified through our initial search, and seven studies were included in our study. In this meta-analysis, the fixed effect and random effects statistical models were used to estimate the synthesized effects of the seven included studies. For every 10 μg/m(3) increase in short-term PM(1) exposure, forced vital capacity (FVC), forced expiratory volume in the first second (FEV(1)), peak expiratory flow (PEF) and maximal mid-expiratory flow (MMEF) decreased by 31.82 mL (95% CI: 20.18, 43.45), 32.28 mL (95% CI: 16.73, 48.91), 36.85 mL/s (95% CI: 15.33, 58.38) and 34.51 mL/s (95% CI: 19.61, 49.41), respectively. For each 10 μg/m(3) increase in long-term PM(1) exposure, FVC, FEV(1), PEF and MMEF decreased by 102.34 mL (95% CI: 49.30, 155.38), 75.17 mL (95% CI: 39.61, 110.73), 119.01 mL/s (95% CI: 72.14, 165.88) and 44.94 mL/s (95% CI: 4.70, 85.18), respectively. Our study provides further scientific evidence for the harmful effects of PM(1) exposure on lung function in children and adolescents, indicating that exposure to PM(1) is detrimental to pulmonary health. To reduce the adverse health effects of air pollution on children and adolescents, effective preventive measures should be taken. MDPI 2022-11-29 /pmc/articles/PMC9740616/ /pubmed/36497960 http://dx.doi.org/10.3390/ijerph192315888 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Zong, Zhiqiang Zhao, Mengjie Zhang, Mengyue Xu, Kexin Zhang, Yunquan Zhang, Xiujun Hu, Chengyang Association between PM(1) Exposure and Lung Function in Children and Adolescents: A Systematic Review and Meta-Analysis |
title | Association between PM(1) Exposure and Lung Function in Children and Adolescents: A Systematic Review and Meta-Analysis |
title_full | Association between PM(1) Exposure and Lung Function in Children and Adolescents: A Systematic Review and Meta-Analysis |
title_fullStr | Association between PM(1) Exposure and Lung Function in Children and Adolescents: A Systematic Review and Meta-Analysis |
title_full_unstemmed | Association between PM(1) Exposure and Lung Function in Children and Adolescents: A Systematic Review and Meta-Analysis |
title_short | Association between PM(1) Exposure and Lung Function in Children and Adolescents: A Systematic Review and Meta-Analysis |
title_sort | association between pm(1) exposure and lung function in children and adolescents: a systematic review and meta-analysis |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740616/ https://www.ncbi.nlm.nih.gov/pubmed/36497960 http://dx.doi.org/10.3390/ijerph192315888 |
work_keys_str_mv | AT zongzhiqiang associationbetweenpm1exposureandlungfunctioninchildrenandadolescentsasystematicreviewandmetaanalysis AT zhaomengjie associationbetweenpm1exposureandlungfunctioninchildrenandadolescentsasystematicreviewandmetaanalysis AT zhangmengyue associationbetweenpm1exposureandlungfunctioninchildrenandadolescentsasystematicreviewandmetaanalysis AT xukexin associationbetweenpm1exposureandlungfunctioninchildrenandadolescentsasystematicreviewandmetaanalysis AT zhangyunquan associationbetweenpm1exposureandlungfunctioninchildrenandadolescentsasystematicreviewandmetaanalysis AT zhangxiujun associationbetweenpm1exposureandlungfunctioninchildrenandadolescentsasystematicreviewandmetaanalysis AT huchengyang associationbetweenpm1exposureandlungfunctioninchildrenandadolescentsasystematicreviewandmetaanalysis |