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Type 1 Tympanoplasty Outcomes between Cartilage and Temporal Fascia Grafts: A Long-Term Retrospective Study

Background: To compare the functional and anatomical results of two different types of grafts in type 1 tympanoplasty (TPL I). Methods: A retrospective comparative bicentric study was conducted on patients treated with TPL I using temporal fascia or tragal cartilage. We evaluated the functional and...

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Autores principales: Ferlito, Salvatore, Fadda, Gianluca, Lechien, Jerome Rene, Cammaroto, Giovanni, Bartel, Ricardo, Borello, Andrea, Cavallo, Giovanni, Piccinini, Francesca, La Mantia, Ignazio, Cocuzza, Salvatore, Merlino, Federico, Achena, Andrea, Brucale, Cristina, Mat, Quentin, Gargula, Stéphane, Fakhry, Nicolas, Maniaci, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740685/
https://www.ncbi.nlm.nih.gov/pubmed/36498572
http://dx.doi.org/10.3390/jcm11237000
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author Ferlito, Salvatore
Fadda, Gianluca
Lechien, Jerome Rene
Cammaroto, Giovanni
Bartel, Ricardo
Borello, Andrea
Cavallo, Giovanni
Piccinini, Francesca
La Mantia, Ignazio
Cocuzza, Salvatore
Merlino, Federico
Achena, Andrea
Brucale, Cristina
Mat, Quentin
Gargula, Stéphane
Fakhry, Nicolas
Maniaci, Antonino
author_facet Ferlito, Salvatore
Fadda, Gianluca
Lechien, Jerome Rene
Cammaroto, Giovanni
Bartel, Ricardo
Borello, Andrea
Cavallo, Giovanni
Piccinini, Francesca
La Mantia, Ignazio
Cocuzza, Salvatore
Merlino, Federico
Achena, Andrea
Brucale, Cristina
Mat, Quentin
Gargula, Stéphane
Fakhry, Nicolas
Maniaci, Antonino
author_sort Ferlito, Salvatore
collection PubMed
description Background: To compare the functional and anatomical results of two different types of grafts in type 1 tympanoplasty (TPL I). Methods: A retrospective comparative bicentric study was conducted on patients treated with TPL I using temporal fascia or tragal cartilage. We evaluated the functional and anatomical results with intergroup and intragroup analyses. Variables predicting long-term success were also evaluated. Results: A total of 142 patients (98 fascia graft vs. 44 cartilage) were initially assessed, with a mean follow-up of 67.1 ± 3.2 months. No significant differences were observed between the two groups on the intergroup analysis of age, gender, ear side, or pre-operative hearing data (all p > 0.05). At the intragroup analysis of auditory outcomes, both groups demonstrated a significant improvement in post-operative air conduction, with greater gain for the fascia group at 6 months follow-up (p < 0.001 for both); however, at long-term follow-up, cartilage demonstrated better stability results (p < 0.001). When comparing the pre-and post-operative air-bone-gap (ABG), both groups showed a significant gain (p < 0.001); the fascia group showed that at 6 months, a greater ABG increase was found, but the difference was not statistically significant (4.9 ± 0.9 dB vs. 5.3 ± 1.2 dB; p = 0.04). On the contrary, the cartilage group at long-term follow-up at 5 years maintained greater outcomes (10 ± 1.6 dB vs. 6.4 ± 2 dB; p < 0.001). Lower age (F = 4.591; p = 0.036) and higher size of perforation (F = 4.820; p = 0.030) were predictors of long-term functional success. Conclusions: The graft material selection should consider several factors influencing the surgical outcome. At long-term follow-up, the use of a cartilage graft could result in more stable audiological outcomes, especially in younger patients or in case of wider perforations.
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spelling pubmed-97406852022-12-11 Type 1 Tympanoplasty Outcomes between Cartilage and Temporal Fascia Grafts: A Long-Term Retrospective Study Ferlito, Salvatore Fadda, Gianluca Lechien, Jerome Rene Cammaroto, Giovanni Bartel, Ricardo Borello, Andrea Cavallo, Giovanni Piccinini, Francesca La Mantia, Ignazio Cocuzza, Salvatore Merlino, Federico Achena, Andrea Brucale, Cristina Mat, Quentin Gargula, Stéphane Fakhry, Nicolas Maniaci, Antonino J Clin Med Article Background: To compare the functional and anatomical results of two different types of grafts in type 1 tympanoplasty (TPL I). Methods: A retrospective comparative bicentric study was conducted on patients treated with TPL I using temporal fascia or tragal cartilage. We evaluated the functional and anatomical results with intergroup and intragroup analyses. Variables predicting long-term success were also evaluated. Results: A total of 142 patients (98 fascia graft vs. 44 cartilage) were initially assessed, with a mean follow-up of 67.1 ± 3.2 months. No significant differences were observed between the two groups on the intergroup analysis of age, gender, ear side, or pre-operative hearing data (all p > 0.05). At the intragroup analysis of auditory outcomes, both groups demonstrated a significant improvement in post-operative air conduction, with greater gain for the fascia group at 6 months follow-up (p < 0.001 for both); however, at long-term follow-up, cartilage demonstrated better stability results (p < 0.001). When comparing the pre-and post-operative air-bone-gap (ABG), both groups showed a significant gain (p < 0.001); the fascia group showed that at 6 months, a greater ABG increase was found, but the difference was not statistically significant (4.9 ± 0.9 dB vs. 5.3 ± 1.2 dB; p = 0.04). On the contrary, the cartilage group at long-term follow-up at 5 years maintained greater outcomes (10 ± 1.6 dB vs. 6.4 ± 2 dB; p < 0.001). Lower age (F = 4.591; p = 0.036) and higher size of perforation (F = 4.820; p = 0.030) were predictors of long-term functional success. Conclusions: The graft material selection should consider several factors influencing the surgical outcome. At long-term follow-up, the use of a cartilage graft could result in more stable audiological outcomes, especially in younger patients or in case of wider perforations. MDPI 2022-11-26 /pmc/articles/PMC9740685/ /pubmed/36498572 http://dx.doi.org/10.3390/jcm11237000 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ferlito, Salvatore
Fadda, Gianluca
Lechien, Jerome Rene
Cammaroto, Giovanni
Bartel, Ricardo
Borello, Andrea
Cavallo, Giovanni
Piccinini, Francesca
La Mantia, Ignazio
Cocuzza, Salvatore
Merlino, Federico
Achena, Andrea
Brucale, Cristina
Mat, Quentin
Gargula, Stéphane
Fakhry, Nicolas
Maniaci, Antonino
Type 1 Tympanoplasty Outcomes between Cartilage and Temporal Fascia Grafts: A Long-Term Retrospective Study
title Type 1 Tympanoplasty Outcomes between Cartilage and Temporal Fascia Grafts: A Long-Term Retrospective Study
title_full Type 1 Tympanoplasty Outcomes between Cartilage and Temporal Fascia Grafts: A Long-Term Retrospective Study
title_fullStr Type 1 Tympanoplasty Outcomes between Cartilage and Temporal Fascia Grafts: A Long-Term Retrospective Study
title_full_unstemmed Type 1 Tympanoplasty Outcomes between Cartilage and Temporal Fascia Grafts: A Long-Term Retrospective Study
title_short Type 1 Tympanoplasty Outcomes between Cartilage and Temporal Fascia Grafts: A Long-Term Retrospective Study
title_sort type 1 tympanoplasty outcomes between cartilage and temporal fascia grafts: a long-term retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740685/
https://www.ncbi.nlm.nih.gov/pubmed/36498572
http://dx.doi.org/10.3390/jcm11237000
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