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Ashkenazi Jewish and Other White APC I1307K Carriers Are at Higher Risk for Multiple Cancers

SIMPLE SUMMARY: APC I1307K has a two-fold increased risk for colorectal cancer in Ashkenazi Jews (AJ) compared to non-Jewish populations. The study aims to demonstrate the prevalence of the APC I1307K variant in the largest cohort of AJ and non-AJ white (NAW) descents described so far. In addition,...

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Detalles Bibliográficos
Autores principales: Forkosh, Esther, Bergel, Michael, Hatchell, Kathryn E., Nielsen, Sarah M., Heald, Brandie, Benson, Ariel A., Friedman, Eitan, Esplin, Edward D., Katz, Lior H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740723/
https://www.ncbi.nlm.nih.gov/pubmed/36497357
http://dx.doi.org/10.3390/cancers14235875