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Investigation of In Vitro and In Vivo Metabolism of α-Amanitin in Rats Using Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometric Method

The purpose of this study is to investigate the difference of in vitro–in vivo correlation of α-amanitin from clearance perspectives as well as to explore the possibility of extra-hepatic metabolism of α-amanitin. First, a liquid chromatography-quadrupole-time-of-flight-mass spectrometric (LC-qTOF-M...

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Detalles Bibliográficos
Autores principales:	Lee, Jiyu, Lee, Byeong ill, Choi, Jangmi, Park, Yuri, Park, Seo-Jin, Park, Minjae, Lim, Jeong-Hyeon, Hwang, Sangsoo, Lee, Jeong-Min, Shin, Young G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740789/ https://www.ncbi.nlm.nih.gov/pubmed/36500706 http://dx.doi.org/10.3390/molecules27238612

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