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HMGB1 Promotes In Vitro and In Vivo Skeletal Muscle Atrophy through an IL-18-Dependent Mechanism

Skeletal muscle atrophy occurs due to muscle wasting or reductions in protein associated with aging, injury, and inflammatory processes. High-mobility group box-1 (HMGB1) protein is passively released from necrotic cells and actively secreted by inflammatory cells, and is implicated in the pathogene...

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Detalles Bibliográficos
Autores principales: Ho, Trung-Loc, Tang, Chih-Hsin, Chang, Sunny Li-Yun, Tsai, Chun-Hao, Chen, Hsien-Te, Su, Chen-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740799/
https://www.ncbi.nlm.nih.gov/pubmed/36497194
http://dx.doi.org/10.3390/cells11233936