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Novel 1,2,3-Triazole-Based Benzothiazole Derivatives: Efficient Synthesis, DFT, Molecular Docking, and ADMET Studies

A new series of 1,2,3-triazole derivatives 5a–f based on benzothiazole were synthesized by the 1,3-dipolar cycloaddition reaction of S-propargyl mercaptobenzothiazole and α-halo ester/amide in moderate to good yields (47–75%). The structure of all products was characterized by (1)H NMR, (13)C NMR, a...

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Detalles Bibliográficos
Autores principales:	Mirjafary, Zohreh, Mohammad Karbasi, Mahdieh, Hesamzadeh, Parsa, Shaker, Hamid Reza, Amiri, Asghar, Saeidian, Hamid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740823/ https://www.ncbi.nlm.nih.gov/pubmed/36500647 http://dx.doi.org/10.3390/molecules27238555

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